Synopsis of recent research by authors named "Nilima Shukla"
- Nilima Shukla's research primarily focuses on the mechanisms underlying vascular smooth muscle cell function and regulation, particularly in the context of endothelial-derived hyperpolarization (EDH) and vascular diseases such as coronary artery bypass graft failure.
- Significant findings include the roles of epoxyeicosatrienoic acids (EETs), hydrogen peroxide (H2O2), and NADPH oxidase in mediating vascular responses, and how these factors may contribute to smooth muscle hyperpolarization and vasodilation.
- Her work also emphasizes the impact of oxidative stress and inflammatory mediators, such as thromboxane A2, on vascular cell behavior and potential therapeutic interventions to mitigate complications from surgical procedures and vascular diseases.
