Thyroid cysts: a new extra-adrenal site of aldosterone synthase expression and increased aldosterone content.

Background: The rapid re-accumulation of fluid following aspiration of thyroid cystic lesions suggests that active transport of sodium and water may be involved in volume regulation of these lesions. In this study we address the possibility that aldosterone may take part in this process.

Subjects And Methods: Thirty-one patients (29 women and two men), with a mean age of 52.