Frequencies and distributions of sex chromosome abnormalities in females with the Turner phenotype: a long-term retrospective study in the southern region of Turkey.

Background/aim: The genetic background of Turner syndrome (TS) is highly variable. The correlation between genotype and phenotype is not yet well understood. The aim of this study was to describe the frequencies and distributions of Turner karyotypes and to discuss the phenotype/genotype relation in a very large group of individuals with TS.

Chromosomal analyses of 1510 couples who have experienced recurrent spontaneous abortions.

In this retrospective study, karyotype results of 1510 couples with a history of recurrent spontaneous abortion were evaluated. The study was conducted at Balcalı Hospital in Adana region of Turkey. For all cases, peripheral blood lymphocytes were cultured for chromosome study using the standard method.

Frequency and types of chromosomal abnormalities in Turkish women with amenorrhea.

Study Objective: To estimate the frequency and the type of chromosomal abnormalities (CA) in patients with primary (PA) and secondary amenorrhea (SA).

Design: This retrospective study was comprised of patients had been referred to our laboratory between 1990 to 2008 and designed as original article.

Setting: Medical Faculty of Cukurova University in Turkey.

Correlation of clinical phenotype with a pericentric inversion of chromosome 9 and genetic counseling.

Objective: To describe the history of 157 carriers of pericentric inversions on chromosome 9 [inv9] with karyotype analyses and evaluate the significance of these findings.

Methods: We studied the incidence, clinical significance, and genetic counseling of inv9 p11;q12, p11;q13, and p11;q21 patients who were referred to our laboratory from various clinics of the Medical Faculty, Cukurova University, Adana, Turkey retrospectively from 157 cases of 15528 cytogenetic analyses collected between May 1993 and February 2007.

Results: We found the incidence of inv9 to be 1.

The role of psychological factors in alopecia areata and the impact of the disease on the quality of life.

Background: The role of psychological factors in the pathogenesis of alopecia areata (AA) has long been the subject of debate. Numerous studies have provided controversial results.

Aim: This case-control study was undertaken to determine the significance of stressful life events and other psychological factors in the etiopathogenesis of AA.

[Psychiatric and psychosocial aspects of chronic renal failure].

Primary treatment modalities of chronic renal failure (CRF) are dialysis and renal transplantation. According to 1997 data there were 10,000 hemodialysis and 1893 continuous ambulatory peritoneal dialysis (CAPD) patients in Turkey. On a yearly basis 360 renal transplantation procedures take place.

Health-related quality of life in Behçet patients with ocular involvement.

Purpose: Health-related quality of life (HRQOL) is an important outcome factor in chronic diseases such as Behçet syndrome. We aimed to investigate the relation of HRQOL to the duration of illness, mental state, and visual acuity of patients with Behçet syndrome.

Methods: We conducted a cross-sectional clinical trial of 45 consecutive Behçet patients with ocular involvement.

Safety of fluoxetine treatment in a case of acute intermittent porphyria.

Acute intermittent porphyria (AIP) is a metabolic disease characterized by recurrent attacks of neurological and psychiatric dysfunction. It is a rare disorder of heme metabolism that usually presents with abdominal pain, gastrointestinal symptoms and autonomic nervous system disturbances. Exposure to certain drugs, dieting, starvation and infection during pregnancy may precipitate AIP attacks.