Publications by authors named "Nilgun Gurses"

Purpose: Nocturnal hypoxia and daytime sleepiness resulting from fragmented sleep may impair the ability of postural stability in subjects with OSA. This study investigates the effect of disease severity on postural stability and whether or not it poses a fall risk in individuals with obstructive sleep apnea (OSA).

Methods: Forty-nine patients with OSA diagnosed by all-night polysomnography (apnea-hypopnea index (AHI) ≥ 5) and aged 51.

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Article Synopsis
  • Late-onset Pompe disease (LOPD) leads to muscle weakness, and this study explored how an 8-week inspiratory muscle training (IMT) program impacts pulmonary function, quality of life, and sleep in eight patients undergoing enzyme replacement therapy (ERT).
  • The study measured pulmonary function before and after IMT, including maximum inspiratory pressure and various quality of life indicators, revealing a significant increase in maximum inspiratory pressure post-training, but no other significant changes in pulmonary function or sleep quality.
  • Overall, the findings indicate that while IMT positively affects maximum inspiratory pressure in LOPD patients on ERT, it does not significantly improve other pulmonary measurements or quality of life and sleep quality metrics.
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Article Synopsis
  • The study aimed to assess the impact of inspiratory and expiratory muscle training on lung function in patients with slowly progressive neuromuscular disease.
  • Participants consisted of 26 patients who were randomly divided into an experimental group undergoing muscle training and a sham group receiving minimal intervention.
  • Results showed significant improvements in muscle strength measured by pressures, but no changes in standard lung function tests, indicating that while muscle strength improved, it did not translate to better overall pulmonary function.
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Objective: To compare the effects of home training programmes, threshold inspiratory muscle training and breathing exercise on spirometry and maximal pressures in patients with muscular dystrophy.

Design: Prospective blinded 12-week study.

Settings: Cardiopulmonary department of university hospital.

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