A Comparative Study to Assess the Add on Effects of Probiotic in Allergic Rhinitis Patients in a Tertiary Care Hospital.

Probiotic intervention may have a promising role in the prevention of AR, in preventing allergic diseases including AR. Probiotics can exert beneficial effects on the host through distinct cellular and molecular pathways, these mechanisms of action may vary from one kind of probiotic to another for the same immune response and may be regulated by a combination of several events. Material and methods- Research site-Tertiary Care Government Hospital and Medical College in a major metropolitan city.

Protective Effect of Rutin and Quercetin against Radiation-induced Genetic Damage in Human Lymphocytes.

Purpose Of The Study: Rutin (RUT) and quercetin (QRT) which are dietary compounds were investigated for their ability to protect against ionizing radiation (IR)-induced genotoxicity in human lymphocytes.

Materials And Methods: The radiation antagonistic potential of RUT and QRT was assessed by alkaline comet and cytokinesis-block micronucleus (CBMN) assay.

Results: Treatment of lymphocytes with RUT and QRT (25 μg/ml) prior exposure to 2 Gy gamma radiation resulted in a significant reduction of frequency of micronuclei as compared to the control set of cells evaluated by CBMN assay.