Publications by authors named "Niler Manuel Segura-Plasencia"
Association of beta blockers and mortality in adults with septic shock: systematic review and meta-analysis of randomized clinical trial.
Front Med (Lausanne)
September 2024
Article Synopsis
- Septic shock remains a serious condition with high rates of morbidity and mortality, particularly affecting heart function, which might be improved through β-blocker therapy to control heart rate and reduce mortality.
- A meta-analysis of ten studies involving 1,121 adults with septic shock showed that β-blockers, especially esmolol, were linked to lower overall mortality rates and better heart performance indicators after 28 days of treatment.
- While the positive results for esmolol were significant, the landiolol subgroup did not demonstrate similar effects, highlighting the need for further research on different β-blockers to understand their varying impacts.
Testosterone levels and risk of newly diagnosed type 2 diabetes mellitus in adult men: systematic review and meta-analysis.
Endocrine
September 2024
Introduction: Testosterone is a metabolically active hormone in males for metabolic homeostasis. Although the coexistence of low testosterone levels and type 2 diabetes mellitus (T2DM) have been associated, there are no reports that evaluate alterations in total testosterone (TT) levels and the risk of newly diagnosed T2DM. This review evaluates this question in adult men with high or low levels of total testosterone (TT), as well as the role played by other hormones such as free testosterone (FT), sex hormone binding globulin (SHBG), dihydrotestosterone (DHT), estrogens and testosterone bioavailable (bT).
View Article and Find Full Text PDFPurpose: To determine the prognosis significance of the TNM clinic stage and the five-year survival rate of patients with primary carcinoma of the gallbladder.
Material And Methods: A descriptive, longitudinal, observational study with a single-box empirical design that evaluated 71 patients with gallbladder cancer who had surgical resection of the neoplasia in the Belén Hospital in Trujillo, Peru between 1966 and 2000.
Results: The mean age of the total series was 61.