Publications by authors named "Nilay Orak"
Article Synopsis
- Cardiovascular risk factors can begin early in life, especially during puberty, and there's a need to understand how sex hormones, insulin resistance, and lipid levels are connected in children.
- The study involved 365 school students aged 8-18, examining how various sex hormones and sex hormone-binding globulin (SHBG) relate to insulin resistance and lipid levels in prepubertal and adolescent boys and girls.
- Findings revealed that estradiol in prepubertal boys was linked to higher insulin resistance and levels, while SHBG in adolescent girls was associated with lower insulin resistance; both groups showed significant connections between sex hormones and HDL-C levels.
Cardiovascular risk starts early in life, yet the patterns of changes in metabolic syndrome (MS) during puberty and normal development have not been completely defined. Sex hormones are shown to play a pivotal role in the modulation of insulin resistance and MS. Our aim is to clarify the relation between sex hormones and MS in normal children and adolescents.
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