Publications by authors named "Nila Kirupaharan"

Purpose: To analyze the accuracy and thoroughness of three large language models (LLMs) to produce information for providers about immune checkpoint inhibitor ocular toxicities.

Methods: Eight questions were created about the general definition of checkpoint inhibitors, their mechanism of action, ocular toxicities, and toxicity management. All were inputted into ChatGPT 4.

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Article Synopsis
  • The study evaluated how accurately and thoroughly three large language models (ChatGPT 4.0, Bard, and LLaMA) could generate information on ocular toxicities related to antibody-drug conjugates (ADCs).
  • Twenty-two specific questions about two ADCs were tested, with responses rated by ocular toxicity experts using a 6-point scale for accuracy and completeness.
  • Results showed that ChatGPT and Bard scored higher in accuracy than LLaMA, while all models demonstrated high completeness, indicating they can effectively handle specialized topics within ophthalmology.
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