Descriptive Epidemiology of Brain and Central Nervous System Tumours: Results from Iran National Cancer Registry, 2010-2014.

Background: Central nervous system (CNS) tumours account for only 1-2% of cancer incidence but are a major reason for mortality and morbidity due to malignancies. Recent studies show an increase in the rate of CNS tumours worldwide, especially in developing countries. Moreover, there is significant heterogeneity in epidemiological patterns worldwide.

En-bloc Resection of a Giant Cell Tumor Causing Cervical Vertebral Collapse.

Giant cell tumors (GCTs) are rare, benign, and locally aggressive primary bone neoplasms. Spine is seldom affected, especially above the level of sacrum. In this report, we describe a case with GCT of the cervical vertebrae which causes collapse of the corpus.

Psychological consideration in patients with cerebral gliomas candidates for intra-operative radiation therapy based on tumor location.

Objective: Intra-operative Radiation Therapy (IORT) is gaining popularity as an adjuvant option to surgical resection, in treatment of glioblastoma multiforme (GBM) for increasing survival rate, which a highly aggressive cerebral tumor with poor prognosis. Τhe authors plan to investigate the effects of IORT combined with surgical resection on the psychological status of these patients based on tumor location.

Subject And Methods: From December 2013 to February 2017, we have enrolled 109 patients with high grade cerebral gliomas, documented by Magnetic Resonance Spectroscopy (MRS).

Deep brain nucleus targeting in Parkinson's disease and essential tremor by image guided surgery using neuronavigation system with tractography and volume of tissue of activated assessment.

Objective: Deep Brain Stimulation (DBS) is an effective surgical approach for treatment of Parkinson's disease (PD), dystonia and essential tremor (ET). Traditionally, DBS is performed using frame-based stereotactic technique. Recently, image guided surgery (IGS) using neuronavigation has gained popularity in neurosurgical procedures.

The role of tranexamic acid in prevention of hemorrhage in major spinal surgeries.

Background: Blood loss that necessitates blood transfusion is one of the most frequent complications of major spinal surgeries. This study has been designed to evaluate the efficacy and safety of prophylactic tranexamic acid (TA) in decreasing perioperative blood loss.

Materials And Methods: From January to August 2011, all the patients who needed major spinal surgeries and aged between 18 and 60-year-old were divided into two groups randomly, the experimental group received 10 mg/kg of TA 20 min after inducing the anesthesia as loading dose followed by 0.

Radioguided surgery using gamma detection probe technology for resection of cerebral glioma.

Objective: Using microsurgical procedures without intraoperative imaging, Gross Total Resection (GTR) has so far only been achieved in less than 30% of all cases. Radio-guided surgery was introduced in the clinical setting in 1985 in an attempt to facilitate intraoperative tumor detection. Because of few studies in literature about this subject, we decided to use gamma probe with the hypothesis that we could increase extent of tumor resection.

Psychological aspects in brain tumor patients: A prospective study.

Objective: Very few studies have utilized specific criteria to assess mental disorders in brain tumor patients, and from them, they are mainly descriptive. The purpose of this study is to examine mental disorders in relation to tumor characteristics and patients' psychosocial factors using DSM-IV (depression, sleep and mood) criteria, among brain tumor patients.

Materials And Methods: From March 2009 to July 2011, 98 patients who surgically treated with intracranial neoplasm were included in this prospective study.