Publications by authors named "Nikos Magkas"

Background: The aim of this work was to evaluate the impact of peritoneal dialysis (PD) on venous congestion, right ventricular function, pulmonary artery systolic pressure (PASP), and clinical functional status in elderly patients with cardiorenal syndrome (CRS) and chronic heart failure (HF).

Methods: A case series of 21 (17 males, age 70 ± 11 years) consecutive patients with HF along with diuretic resistance and right ventricular dysfunction (median renal failure duration 60 months, range 13-287 months, mean ejection fraction 36 ± 11%) having been engaged in PD; 76% of the patients were under automated peritoneal dialysis (APD), whereas the rest were under continuous ambulatory PD (CAPD). Patients' PASP and central venous pressure (CVP) - through compression sonography - and body weight were evaluated before initiating the PD program and at 6 and 12 months.

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Article Synopsis
  • The study aimed to explore if carotid-to-femoral pulse wave velocity (cf-PWV), an indicator of arterial stiffness, is linked to coronary artery disease (CAD) and diastolic dysfunction in elderly high-risk patients compared to younger individuals.
  • Data from 192 high-risk patients who underwent coronary artery angiography were analyzed, measuring cf-PWV and indices of diastolic dysfunction through echocardiography.
  • Results indicated that while cf-PWV was associated with CAD and diastolic dysfunction in patients under 65, this correlation was not observed in elderly patients, suggesting arterial stiffness measurement may not be clinically useful for this older demographic.
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Objectives: Accumulating evidence suggests a direct role of Uric Acid (UA) on Left Ventricular (LV) diastolic function in chronic kidney disease and Heart Failure (HF) patients. Recently, UA has been linked to LV Hypertrophy (LVH) and Diastolic Dysfunction (DD) in women with preserved Ejection Fraction (pEF) but not in corresponding men. We sought to assess if UA could predict indices of DD in hypertensive subjects with pEF independently of gender.

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