[Comparative analysis of the effectiveness of SF-MPQ-2 and VAS for assessing the severity of pain syndrome in dental patients in the postoperative period].

Objective: Conducting a comparative analysis of the effectiveness of the Short-Form McGill Pain Questionnaire-2 (SF-MPQ-2) and the Visual Analogue Scale (VAS) for assessing the severity of pain syndrome in dental patients in the postoperative period in dynamics.

Material And Methods: The study included 51 patients who received dental surgical treatment. Two groups of patients were formed, depending on the type of surgery and the degree of trauma of the operation.

A Genome-Wide Association Study Reveals a -Centered Molecular Network Associated with Alcohol Dependence and Related Clinical Measures.

At least 50% of factors predisposing to alcohol dependence (AD) are genetic and women affected with this disorder present with more psychiatric comorbidities, probably indicating different genetic factors involved. We aimed to run a genome-wide association study (GWAS) followed by a bioinformatic functional annotation of associated genomic regions in patients with AD and eight related clinical measures. A genome-wide significant association of rs220677 with AD (-value = 1.

[An associations of possible genetic risk markers for Internet addiction with childhood trauma experience and personality traits in young adults : preliminary results].

Objective: To study was to test an associations of the preliminary genetic risk markers for Internet addiction (IA) with clinical, psychological and personality characteristics, taking into account the childhood traumatic experience, in 44 IA persons compared with 120 healthy individuals.

Material And Methods: The study included 164 participants: 44 individuals with IZ (group IZ), male and female, aged 16 to 30 years in the absence of diagnoses of mental health problems. diseases from rubrics F00-09 and F20-29 (ICD-10) and 120 healthy (control group).

[Family history of affective disorders, the gender factor and clinical characteristics of depression].

Objective: Analysis of clinical features of development and course of depression in patients with FH of mood disorders taking into account sex differences.

Material And Methods: This multicenter cross-sectional study included patients over 18 years of age with depressive episode/recurrent depressive disorder. Clinical characteristics of depression, presence of comorbid mental illness and family history (FH) information were obtained in a structured clinical interview.

[Clinical and psychological features of people with internet dependence: experience of a pilot study].

Objective: The prevalence of Internet addiction (IA) is growing steadily, especially among the younger generation. The purpose of this multicenter study was to investigate the socio-demographic characteristics, clinical varieties, and profile of psychopathological symptoms of mental disorders in patients with IA.

Material And Methods: The study included 2 groups: the main group consisted of 44 people, aged 16 to 34 years, average age 22.

Opening up new horizons for psychiatric genetics in the Russian Federation: moving toward a national consortium.

We provide an overview of the recent achievements in psychiatric genetics research in the Russian Federation and present genotype-phenotype, population, epigenetic, cytogenetic, functional, ENIGMA, and pharmacogenetic studies, with an emphasis on genome-wide association studies. The genetic backgrounds of mental illnesses in the polyethnic and multicultural population of the Russian Federation are still understudied. Furthermore, genetic, genomic, and pharmacogenetic data from the Russian Federation are not adequately represented in the international scientific literature, are currently not available for meta-analyses and have never been compared with data from other populations.

[Infrared spectroscopy of the enamel in dental fluorosis].

Structural relationships in orthophosphate (PO4)3-, carbonate (CO3)2-, and hydroxyl (OH)- groups were studied in 2 teeth with grave fluorosis manifestations, removed for orthodontic indications, by infrared spectroscopy. Two intact teeth were examined for control. The findings evidence ar elevated protein level in fluorosis-involved dental enamel and impaired enamel microstructure; this may be explained by specific features of fluorosis clinical manifestation and by increased enamel permeability in grave fluorosis.

[The UDK-87 device for the electrodiagnosis of caries].

A new scheme of an device for electrodiagnosis of caries is suggested, based on studies of dental hard tissue electric resistance. A highly sensitive M136 gage with 0.5 microA complete deviation current is employed in the scheme, this permitting measurements of high electric resistance of dental hard tissues within a range of 1-200 M omega, painless for patients.

[The effect of calcium glycerophosphate and Remodent on the dental enamel permeability in dogs with fluorosis].

In 14 dogs aged 6 months with severe fluorosis, the authors studied the effects of intake of calcium glycerophosphate and local remodent application on 45Ca enamel incorporation and the depth of its penetration into the dental hard tissues. The treatment led to a substantial decrease in both enamel 45Ca accumulation and the depth of its penetration under severe fluorosis. Combined use of the drugs was more beneficial in terms of enamel 45Ca permeability.

[The effect of various concentrations of hydrochloric acid solutions on the enamel permeability for 45Ca in experimental fluorosis].

In 96 months-old dogs with light fluorosis the effect of 10% HCl solution and the mixture of 36% HCl solution with concentrated HCl (1:2) on 45Ca incorporation into the superficial and deep enamel layers, and its penetration into the dental hard tissues. The increase in HCl concentration was directly related to enamel 45Ca incorporation and the depth of its penetration in fluorosis-afflicted teeth. Under effect of 12% HCl solution 45Ca penetrated across the whole enamel reaching the dentin.

[The Ca and P content of various layers of human dental enamel in differing manifestations of fluorosis].

X-ray spectral microanalysis was applied to study Ca and P contents in superficial, intermedial and deep enamelum zones in 15 human teeth with different fluorosis manifestations which were extracted for orthodontic purposes. In 3rd grade fluorosis, detected were a statistically reliable decrease in Ca content in enamelum superficial zone and a tendency of its depleting in deep zones. Ca/P ratio was also lowered that indicated mineralization impairment in solid tissues of the teeth.