Publications by authors named "Nikolina Brcina"

Article Synopsis
  • This study explored altered brain activity in patients with idiopathic REM-sleep behavior disorder (RBD) during movement tasks, comparing them with healthy controls.
  • Thirteen RBD patients and 13 healthy participants underwent fMRI while performing hand movements, revealing no performance differences but some distinct activation patterns in the RBD group.
  • The results suggest that increased brain activation and altered connectivity in RBD patients may be early signs of compensatory changes aimed at maintaining motor skills.
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Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by the loss of physiological atonia of skeletal muscles with abnormal behavior during dream sleep. RBD may be the initial manifestation of neurodegenerative diseases, particularly of α-synucleinopathies such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). However, gauging the individual risk of subsequent phenoconversion and making assumptions on the type of disease that may subsequently follow RBD is challenging.

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Objective: We wanted to primarily examine the knowledge, attitudes and behaviour of parents and health workers (community nurses and paediatricians) regarding child injuries in order to understand the essence of the problem and to find out the most common misconceptions.

Methods: Respondents were tested through an anonymous, self-administered questionnaire and all p values below 0.05 were considered significant.

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Background: This retrospective study was designed to evaluate whether patients with hydrocephalus associated with central nervous system (CNS) anomalies, compared with patients with hydrocephalus and absent CNS anomalies, present with significantly higher rate of postoperative complications, including more serious clinical presentation, increased life threat, and higher postoperative or late mortality rate.

Methods: We performed a retrospective study using medical records of 100 patients of pediatric and adolescent age (0-18 years) between 2004 and 2010 treated with operative cerebrospinal fluid (CSF) shunt placement.

Results: In both groups of patients, there were 43 postoperative complications, including 12 mechanical obstructions of the CSF drainage systems, 13 disconnections, 11 dislocations of proximal catheter, 6 inflammatory complications (meningitis), and 1 latex allergy.

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