Global taxonomic, functional, and phylogenetic diversity of bees in apple orchards.

An essential prerequisite to safeguard pollinator species is characterisation of the multifaceted diversity of crop pollinators and identification of the drivers of pollinator community changes across biogeographical gradients. The extent to which intensive agriculture is associated with the homogenisation of biological communities at large spatial scales remains poorly understood. In this study, we investigated diversity drivers for 644 bee species/morphospecies in 177 commercial apple orchards across 33 countries and four global biogeographical biomes.

Untargeted proteomic differences between clinical strains of methicillin-sensitive and methicillin-resistant Staphylococcusaureus.

Staphylococcus aureus is a common disease-causing bacterium that has developed resistances to a wide variety of antibiotics. This increasing antibiotic resistance has made management of these infections difficult. A better understanding of the general differences among clinical S.

Tunable zero-energy Dirac and Luttinger nodes in a two-dimensional topological superconductor.

Cooper pairing in ultrathin films of topological insulators, induced intrinsically or by proximity effect, can produce an energetically favorable spin-triplet superconducting state. The spin-orbit coupling acts as an SU(2) gauge field and stimulates the formation of a spin-current vortex lattice in this superconducting state. Here we study the Bogoliubov quasiparticles in such a state and find that the quasiparticle spectrum consists of a number of Dirac nodes pinned to zero energy by the particle-hole symmetry.

The Cell Wall, Cell Membrane and Virulence Factors of and Their Role in Antibiotic Resistance.

Antibiotic resistant strains of bacteria are a serious threat to human health. With increasing antibiotic resistance in common human pathogens, fewer antibiotics remain effective against infectious diseases. is a pathogenic bacterium of particular concern to human health as it has developed resistance to many of the currently used antibiotics leaving very few remaining as effective treatment.

Untargeted lipidomic differences between clinical strains of methicillin-sensitive and methicillin-resistant .

Background: is a common cause of infectious diseases in humans. It has become resistant to many antibacterial agents making management of infections difficult. A better understanding of differences among strains that are sensitive and resistant to antibiotics may offer insights into the resistant phenotype and identify new antimicrobial targets.

Root Resorptions on Adjacent Teeth Associated with Impacted Maxillary Canines.

Aim: Through the use of CBCT images, many unidentified features of impacted canines can be easily resolved. The potential collision of impacted maxillary canines and adjacent teeth could lead to root resorption (RR). The aim of this study is to examine the prevalence, location and severity of RR on adjacent teeth caused by impacted maxillary canines and the association between the adjacent teeth and the features of maxillary impacted canines on CBCT.

Weyl-mediated helical magnetism in NdAlSi.

Emergent relativistic quasiparticles in Weyl semimetals are the source of exotic electronic properties such as surface Fermi arcs, the anomalous Hall effect and negative magnetoresistance, all observed in real materials. Whereas these phenomena highlight the effect of Weyl fermions on the electronic transport properties, less is known about what collective phenomena they may support. Here, we report a Weyl semimetal, NdAlSi, that offers an example.

The in vitro antibacterial effect of permethrin and formaldehyde on Staphylococcus aureus.

Antibiotic-resistant strains of bacteria such as methicillin-resistant Staphylococcus aureus are a threat to human health, and effective treatment options against them are needed. This study aimed to determine whether the insecticide permethrin was capable of inhibiting the growth of S. aureus or if some other component of a permethrin cream was responsible for a decrease in scabies associated bacterial infection previously observed.

Formaldehyde as an alternative to antibiotics for treatment of refractory impetigo and other infectious skin diseases.

: Antibiotic-resistant strains of bacteria are an increasing problem in hospitals and in the community. This has resulted in bacterial infections such as impetigo becoming difficult to treat. Alternative treatment options are needed.

Concurrent, Performance-Based Methodology for Increasing the Accuracy and Certainty of Short-Term Neural Prediction Systems.

Accurate prediction of the short time series with highly irregular behavior is a challenging task found in many areas of modern science. Such data fluctuations are not systematic and hardly predictable. In recent years, artificial neural networks have widely been exploited for those purposes.

Screened moments and extrinsic in-gap states in samarium hexaboride.

Samarium hexaboride (SmB) is a Kondo insulator, with a narrow gap due to hybridization between localized and conduction electrons. Despite being an insulator, many samples show metal-like properties. Rare-earth purification is exceedingly difficult, and nominally pure samples may contain 2% or more of impurities.

In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1.

Background: We use our earlier experimental studies of the catalytic mechanism of DNA methyltransferases to prepare in silico a family of novel mechanism-based inhibitors of human Dnmt1. Highly specific inhibitors of DNA methylation can be used for analysis of human epigenome and for the creation of iPS cells.

Results: We describe a set of adenosyl-1-methyl-pyrimidin-2-one derivatives as novel mechanism-based inhibitors of mammalian DNA methyltransferase Dnmt1.

Development of a multiperspective optical measuring system for investigating decaying switching arcs at the nozzle exit of circuit breakers.

High-voltage gas circuit breakers, which play an important role in the operation and protection of the power grid, function by drawing an arc between two contacts and then extinguishing it by cooling it using a transonic gas flow. Improving the design of circuit breakers requires an understanding of the physical processes in the interruption of the arc, particularly during the zero crossing of the alternating current (the point in time when the arc can be interrupted). Most diagnostic techniques currently available focus on measurement of current, voltage, and gas pressure at defined locations.

Transcriptome study and identification of potential marker genes related to the stable expression of recombinant proteins in CHO clones.

Background: Chinese hamster ovary (CHO) cells have become the host of choice for the production of recombinant proteins, due to their capacity for correct protein folding, assembly, and posttranslational modifications. The most widely used system for recombinant proteins is the gene amplification procedure that uses the CHO-Dhfr expression system. However, CHO cells are known to have a very unstable karyotype.

Pharyngeal Airway Changes after Bimaxillary Orthognathic Surgery--Preliminary Results.

Introduction: Dentofacial deformity, a deviation from normal facial proportions and dental relationships, is corrected by jaw repositioning in all three spatial planes, which changes the position and tension of the surrounding tissues, bones and muscles. These changes may also affect the dimensions of the pharyngeal airways (PA).

Objective: The aim of this study was to evaluate and compare three-dimensional PA changes in patients treated by a combination mandibular set-back/maxillary advancement versus patients that had bimaxillary advancement with genioplasty.

LAMP assay and rapid sample preparation method for on-site detection of flavescence dorée phytoplasma in grapevine.

In Europe the most devastating phytoplasma associated with grapevine yellows (GY) diseases is a quarantine pest, flavescence dorée (FDp), from the 16SrV taxonomic group. The on-site detection of FDp with an affordable device would contribute to faster and more efficient decisions on the control measures for FDp. Therefore, a real-time isothermal LAMP assay for detection of FDp was validated according to the EPPO standards and MIQE guidelines.

Interaction driven subgap spin exciton in the Kondo insulator SmB6.

Using inelastic neutron scattering, we map a 14 meV coherent resonant mode in the topological Kondo insulator SmB6 and describe its relation to the low energy insulating band structure. The resonant intensity is confined to the X and R high symmetry points, repeating outside the first Brillouin zone and dispersing less than 2 meV, with a 5d-like magnetic form factor. We present a slave-boson treatment of the Anderson Hamiltonian with a third neighbor dominated hybridized band structure.

Superconductivity at the border of electron localization and itinerancy.

The superconducting state of iron pnictides and chalcogenides exists at the border of anti-ferromagnetic order. Consequently, these materials could provide clues about the relationship between magnetism and unconventional superconductivity. One explanation, motivated by the so-called bad metal behaviour of these materials proposes that magnetism and superconductivity develop out of quasi-localized magnetic moments that are generated by strong electron-electron correlations.

Cephalometric assessment of maxillary length in Serbian children with skeletal class III.

Background/aim: Malocclusion of skeletal class III is a complex irregularity of sagittal inter-jaw relationship, which is due to irregularities of sagittal position of one or both of the jaw bones, which is often associated with disproportionate ratio of their length. The aim of this study was to determine whether the length of the jaw of children with skeletal class III in the period of mixed dentition was changed.

Methods: Fifty children with skeletal class III and the same number of those with skeletal class I, of both sexes, have been selected on the basis of cephalometric analysis of profile tele-x-ray of the head.

Fractional topological insulators of Cooper pairs induced by the proximity effect.

Certain insulating materials with strong spin-orbit interaction can conduct currents along their edges or surfaces owing to the nontrivial topological properties of their electronic band structure. This phenomenon is somewhat similar to the integer quantum Hall effect of electrons in strong magnetic fields. Topological insulators analogous to the fractional quantum Hall effect are also possible, but have not yet been observed in any material.

[Analysis of variation of sagittal position of the jaw bones in skeletal Class III malocclusion].

Background/aim: Skeletal Class III malocclusion is a discrepancy in the sagittal jaw relationship, due to imbalances in their development and/or position, resulting in the dominant appearance of the lower jaw in facial profile. The aim of this study was to determine variations in the sagittal position of the jaw bones to the cranial base in subjects with skeletal Class III, for the earliest possible diagnosis of malocclusion.

Methods: Fifty children and as many adults with skeletal Class III, both sexes, were examined and selected, based on the findings of sagittal interjaw relationship (ANB) < or = 0 degrees from the cephalometric analysis of tele-x-ray profile head shots.

Charge and spin fractionalization in strongly correlated topological insulators.

We construct an effective topological Landau-Ginzburg theory that describes general SU(2) incompressible quantum liquids of strongly correlated particles in two spatial dimensions. This theory characterizes the fractionalization of quasiparticle quantum numbers and statistics in relation to the topological ground-state symmetries, and generalizes the Chern-Simons, BF ('background field') and hierarchical effective gauge theories to an arbitrary representation of the SU(2) symmetry group. We mainly focus on fractional topological insulators with time-reversal symmetry, which are treated as SU(2) generalizations of the quantum Hall effect.

Real-time PCR for specific detection of three phytoplasmas from the apple proliferation group.

In this chapter, we describe a real-time PCR detection system for fast, reliable, specific, and sensitive detection and discrimination of 'Candidatus Phytoplasma mali', 'Ca. P. prunorum', and 'Ca.

Automated DNA extraction for large numbers of plant samples.

The method described here is a rapid, total DNA extraction procedure applicable to a large number of plant samples requiring pathogen detection. The procedure combines a simple and quick homogenization step of crude extracts with DNA extraction based upon the binding of DNA to magnetic beads. DNA is purified in an automated process in which the magnetic beads are transferred through a series of washing buffers.

Evaluation of a prevention programme efficiency for patients with fixed orthodontic appliances.

Background/aim: Orthodontic treatment enables the establishment of functional occlusion and improvement of oral health, however, it increases the risk of periodontal disease development. The aim of this paper was to examine the efficiency of the applied programme for the prevention of gingivitis in children undergoing the fixed orthodontic appliance therapy and to determine the most efficient devices and techniques for maintaining oral hygiene during orthodontic treatment.

Methods: The study included 80 patients of both genders--60 patients comprised the experimental group and 20 patients comprised the control group.