Rapid Reversal of Carbapenemase-Producing Epidemiology from - to -harbouring Isolates in a Greek Tertiary Care Hospital.

Carbapenemase-producing strains present a specific geographical distribution regarding the type of carbapenemase-encoding genes that they harbor. For more than twenty years, VIM-type enzymes were the only major carbapenemases that were detected among isolates in Greece until the emergence of NDM-1-encoding in early 2023. In the present study, we present the rapid reversal of the carbapenemase-producing epidemiology from - to -harbouring isolates that occurred in our hospital since then.

Probable Three-Species In Vivo Transfer of in a Single Patient in Greece: Occurrence of NDM-1-Producing , , and .

NDM carbapenemase-encoding genes disseminate commonly among Enterobacterales through transferable plasmids carrying additional resistance determinants. Apart from the intra-species dissemination, the inter-species exchange of plasmids seems to play an additional important role in the spread of . We here present the genetics related to the isolation of three species (, , and ) harboring the gene from a single patient in Greece.

In vitro activity of eravacycline and cefoperazone/ sulbactam against extensively-drug resistant and pan-drug resistant Acinetobacter baumannii isolates from a tertiary hospital in Greece.

We evaluated the in vitro activity of eravacycline and cefoperazone/sulbactam against 42 XDR and 58 PDR Acinetobacter baumannii isolates from blood and bronchoalveolar infections. The minimum and maximum MICs for eravacycline were 0.125 and 4 mg/L, respectively.