Publications by authors named "Nikole Scappe"
Article Synopsis
- Excessive mucocutaneous bleeding (MCB) significantly affects the physical and mental health of individuals living with it, and there's a need for more research on various bleeding disorders.
- The National Hemophilia Foundation and American Thrombosis and Hemostasis Network are developing a research plan by consulting stakeholders to determine priorities and create specific research questions.
- Expert working groups identified 38 key research questions focused on MCB biology and different bleeding disorders, emphasizing the importance of collaboration and innovative treatments in future studies.
von Willebrand disease (VWD) is associated with significant morbidity as a result of excessive mucocutaneous bleeding. Early diagnosis and treatment are important to prevent and treat these symptoms. We systematically reviewed the accuracy of diagnostic tests using different cutoff values of von Willebrand factor antigen (VWF:Ag) and platelet-dependent von Willebrand factor (VWF) activity assays in the diagnosis of VWD.
View Article and Find Full Text PDFBackground: von Willebrand disease (VWD) is the most common inherited bleeding disorder known in humans. Accurate and timely diagnosis presents numerous challenges.
Objective: These evidence-based guidelines of the American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), the National Hemophilia Foundation (NHF), and the World Federation of Hemophilia (WFH) are intended to support patients, clinicians, and other health care professionals in their decisions about VWD diagnosis.