Mimics of Pincer Ligands: An Accessible Phosphine-Free -(Pyrimidin-2-yl)-1,2-azole-3-carboxamide Framework for Binuclear Pd(II) Complexes and High-Turnover Catalysis in Water.

We report for the first time cyclic phosphine-free "head to tail" N,N,N pincer-like (pincer complexes mimicking) -(pyrimidin-2-yl)-1,2-azole-3-carboxamide Pd(II) complexes with deprotonated amide groups as high-turnover catalysts (TON up to 10, TOF up to 1.2 × 10 h) for cross-coupling reactions on the background of up to quantitative yields under Green Chemistry conditions. The potency of the described catalyst family representatives was demonstrated in Suzuki-Miyaura, Mizoroki-Heck, and Sonogashira reactions on industrially practical examples.

Pathways of ion-molecular interactions of nucleogenic phenyl cations with the nucleophilic centers of picolines.

Background: The nuclear-chemical method brought unique opportunity for synthesis of unknown and hardly available organic compounds. Presence of tritium labeling allows one-step preparation of radioactive markers for the investigation of chemical and biological processes.

Methods: The ion-molecular reactions of nucleogenic phenyl cations with 4-picoline have been carried out.