Publications by authors named "Nikolaus Schneider"
Introduction: During extracorporeal membrane oxygenation (ECMO) systemic anticoagulation with unfractionated heparin (UFH) is standard-of-care. However, there is uncertainty regarding optimal anticoagulation monitoring strategies.
Methods: We retrospectively investigated venovenous and venoarterial ECMO patients at the medical ICUs at the Medical University of Graz, Austria.
Article Synopsis
- A study analyzed 581 cases of acute poisoning admitted to a medical ICU in Austria from 2007 to 2021, revealing that suicidal intent was the primary cause in nearly half of the cases and that 46.6% involved mixed intoxications.
- The research utilized various data sources, including ICU records and autopsy reports, and found that while ICU mortality was low at 4.1%, pre-existing psychiatric illnesses had increased significantly among patients over time.
- Compared to a historical dataset from 1992-1996, there was a notable shift away from gastric lavage as a detoxification method and a rise in alternative techniques, indicating changes in treatment approaches for intoxicated patients.
Article Synopsis
- Carbohydrate-deficient transferrin (CDT) and the Anttila-Index are biomarkers that may indicate heavy alcohol use and could predict delirium and mortality in critically ill patients.
- In a study of 343 ICU patients, 35% experienced delirium, with those affected showing significantly higher levels of CDT and Anttila-Index upon admission.
- Higher CDT and Anttila-Index levels were linked to both the occurrence of delirium and longer duration of delirium, as well as increased hospital mortality risk.