Comparative genome characterization of the periodontal pathogen Tannerella forsythia.

Background: Tannerella forsythia is a bacterial pathogen implicated in periodontal disease. Numerous virulence-associated T. forsythia genes have been described, however, it is necessary to expand the knowledge on T.

Genomes of the wild beets Beta patula and Beta vulgaris ssp. maritima.

We present draft genome assemblies of Beta patula, a critically endangered wild beet endemic to the Madeira archipelago, and of the closely related Beta vulgaris ssp. maritima (sea beet). Evidence-based reference gene sets for B.

A General Protein Glycosylation Gene Cluster Encodes the Species-Specific Glycan of the Oral Pathogen : -Glycan Biosynthesis and Immunological Implications.

The cell surface of the oral pathogen is heavily glycosylated with a unique, complex decasaccharide that is -glycosidically linked to the bacterium's abundant surface (S-) layer, as well as other proteins. The S-layer glycoproteins are virulence factors of and there is evidence that protein glycosylation underpins the bacterium's pathogenicity. To elucidate the protein -glycosylation pathway, genes suspected of encoding pathway components were first identified in the genome sequence of the ATCC 43037 type strain, revealing a 27-kb gene cluster that was shown to be polycistronic.