Exposure to perfluoroalkyl substances during fetal life and hospitalization for infectious disease in childhood: A study among 1,503 children from the Odense Child Cohort.

Introduction: The immunosuppressive properties of PFASs are widely recognized. Early-life exposure to PFAS has been linked to reduced immune response to childhood vaccinations and increased rates of common infectious diseases, but implications for hospitalizations are unclear.

Objectives: To investigate the association between maternal serum concentrations of five PFASs during pregnancy and the child's rate of hospitalization due to common infectious diseases between birth and 4 years of age.

Breastfeeding and Infections in Early Childhood: A Cohort Study.

Background: Studies on the association between breastfeeding and infections in children beyond the first year of life reveal conflicting results. In a population-based birth cohort, we investigated whether the duration of breastfeeding was associated with the number of hospitalizations due to infection and symptoms of infection at home.

Methods: In the Odense Child Cohort, text message questionnaires were used to register information on breastfeeding (weekly until end of weaning) and symptoms of infection (biweekly; 12-36 months of age).

Birth Season and Infection Risk Among Children Under 5 Years Old: A Study of Hospital Admissions and Short Message Service-reported Symptoms at Home.

Background: The season in which a child is born may affect the immune system development and thereby influence the risk of infections. In this study, we examined the associations between birth season and the risk of hospital admission or symptoms associated with a wide range of infections.

Methods: This study is a prospective cohort study of 2434 children with an average follow-up of 3.

Cord serum 25-hydroxyvitamin D is not associated with cranial anthropometrics in infants up to 6 months of age. An Odense Child Cohort study.

Skull changes are poorly described in vitamin D insufficiency [serum 25-hydroxyvitamin D (s-25(OH)D) 25-50 nmol/L]. We aimed to investigate factors associated with cranial anthropometrics in infants, especially s-25(OH)D. In infants 2.

Association Between Mode of Delivery and Risk of Infection in Early Childhood: A Cohort Study.

Background: Infections are the leading cause of morbidity and mortality in children. Caesarean section as a potential risk factor for infection has recently gained interest. Delivery by caesarean section has increased greatly, with nonmedical reasons playing an increasing role.

Infant Respiratory Tract Infections or Wheeze and Maternal Vitamin D in Pregnancy: A Systematic Review.

Backgrounds: Respiratory tract infections (RTIs) are a common cause of morbidity and mortality in young children and can be associated with wheeze. Vitamin D can have a protective role against RTI.

Materials And Methods: A systematic search of PubMed, Embase and the Cochrane library was performed.

Association between prenatal exposure to perfluorinated compounds and symptoms of infections at age 1-4years among 359 children in the Odense Child Cohort.

Introduction: Perfluorinated alkylated substances (PFAS) are persistent industrial chemicals that have resulted in global environmental exposures. Previous epidemiological studies have reported possible effects on the immune system after developmental PFAS exposure, but the possible impact on childhood infectious disease is unclear.

Objectives: To investigate the association between prenatal exposure to PFAS and symptoms of infections at age 1-4years.

Outbreak of Pseudomonas aeruginosa bacteraemia in a haematology department.

Introduction: Infection by Pseudomonas aeruginosa represents a major cause of morbidity and mortality among immunocompromised patients. In Denmark, an increase in P. aeruginosa isolates from blood cultures from a haematology department prompted a hygienic audit in 2007.

Atrioventricular septal defects among infants in Europe: a population-based study of prevalence, associated anomalies, and survival.

Objective: To describe the epidemiology of chromosomal and non-chromosomal cases of atrioventricular septal defects in Europe.

Methods: Data were obtained from EUROCAT, a European network of population-based registries collecting data on congenital anomalies. Data from 13 registries for the period 2000-2008 were included.

Seismic evidence for overpressured subducted oceanic crust and megathrust fault sealing.

Water and hydrous minerals play a key part in geodynamic processes at subduction zones by weakening the plate boundary, aiding slip and permitting subduction-and indeed plate tectonics-to occur. The seismological signature of water within the forearc mantle wedge is evident in anomalies with low seismic shear velocity marking serpentinization. However, seismological observations bearing on the presence of water within the subducting plate itself are less well documented.