The degree of oxidative stress is associated with major adverse effects after lung resection: a prospective study.

Objective: This prospective randomized study was conducted in order to define the contribution of the generated oxygen and nitrogen reactive species on postlobectomy morbidity and mortality.

Patients And Methods: Between 2001 and 2003, 132 patients with non-small cell lung cancer (NSCLC) were prospectively studied. The patients were grouped according to one-lung ventilation (OLV) use or not and to the duration of lung's atelectasis.

Molecular markers in gastric cancer: can p53 and bcl-2 protein expressions be used as prognostic factors?

Background: The prognostic value of p53 and bcl-2 protein expressions in gastric cancer is still unclear, as shown by the discordant results still reported in the literature.

Patients And Methods: In this study, p53 and bcl-2 protein expressions were investigated by immunohistochemistry and correlated with various clinicopathological parameters and survival, in a series of 52 gastric cancer patients who underwent potentially curative gastrectomy.

Results: p53 expression was observed in 34 patients (65.