Effect of ketorolac 0.5% drops on patients' pain perception during intravitreal injection procedure.

Purpose: To evaluate the analgesic effect of ketorolac 0.5% drops during the intravitreal injection procedure.

Methods: Thirty patients (n=30) received topical ketorolac 0.

Pars plana vitrectomy in the treatment of severe complicated toxoplasmic retinochoroiditis.

Purpose: To present the anatomic and functional results of pars plana vitrectomy performed in severe complicated toxoplasmic retinochoroiditis.

Methods: Three patients, 2 women and 1 man aged 57, 22, and 57 years, are presented. The first patient was under immunosuppressive therapy for dermatomyositis and underwent diagnostic/therapeutic vitrectomy for severe toxoplasmic panuveitis with dense vitritis.

Decreased contrast sensitivity in children and adolescents with type 1 diabetes mellitus.

Purpose: To evaluate contrast sensitivity in children and adolescents with diabetes mellitus without evidence of diabetic retinopathy.

Methods: Sixty patients with insulin-dependent diabetes mellitus (age range: 8 to 18 years) were studied. Their contrast sensitivity scores were obtained using the CSV-1000 device (Vector Vision, Dayton, OH) for four spatial frequencies and were compared with v scores of 45 age-matched and gender-matched "healthy" patients.

Tear analysis of ascorbic acid, uric acid and malondialdehyde with capillary electrophoresis.

Tears have a significant role in antioxidant defense in ocular tissues and since their collection is quick and noninvasive, their analysis would facilitate monitoring of pathophysiological changes. However, their low volume and low content of antioxidants makes analysis difficult; methods of high sensitivity are needed. In this paper, we present a method for tear analysis of two antioxidant molecules (ascorbic and uric acid) and of a lipid peroxidation indicator (malondialdehyde) with capillary electrophoresis.

Apoptotic mechanisms within the retina in Staphylococcus epidermidis experimental endophthalmitis.

Aim: To investigate the potential involvement of apoptosis and its regulators Bcl-2, Bax, and Fas within the retina in Staphylococcus epidermidis experimental endophthalmitis.

Methods: Endophthalmitis was induced in 48 male Lewis rats by unilateral 25-mircrol intravitreal injection of 7,000 viable organisms of slime-producing S. epidermidis strain ATCC 35983 (experimental group).

Non-invasive detection of antibiotics and physiological substances in the aqueous humor by Raman spectroscopy.

Background And Objectives: Laser Raman spectroscopy is an inelastic light scattering technique able to characterize molecules in aqueous environments. The purpose of this work is to develop a non-contact and non-invasive spectroscopic method to identify and eventually quantify the presence of medicines (e.g.

Expression of TNF-alpha, IL-1beta, and IFN-gamma in Staphylococcus epidermidis slime-positive experimental endophthalmitis is closely related to clinical inflammatory scores.

Purpose: The purpose of this study was to investigate the expression of inflammatory cytokines TNF-alpha, IL-1beta, and IFN-gamma in the vitreous after experimentally induced endophthalmitis by a Staphylococcus epidermidis slime-producing strain.

Methods: Seventy-two experimental Lewis rats received an intravitreal injection of 7000 viable organisms of Staphylococcus epidermidis slime-producing ATCC strain 35983, while 72 control rats received an intravitreal injection of sterile normal saline. Eyes were graded daily for signs of clinical inflammation and were removed 6, 12, 24, 48, 72 h, and 7 days after injection.