Publications by authors named "Nikolaos K Katsilambros"
Chronic exposure of human glomerular epithelial cells to high glucose concentration results in modulation of high-affinity glucose transporters expression.
Dimitrios-Anestis D Moutzouris Paraskevi V Kitsiou Argiris A Talamagas Garyfallia I Drossopoulou Theodore I Kassimatis Nikolaos K Katsilambros
Ren Fail
April 2008
Article Synopsis
- GLUTs are membrane proteins that help transport glucose, and this study focuses on their expression in kidney cells under diabetic conditions, specifically looking at GLUTs 1, 3, and 4.
- Researchers used an immortalized HGEC cell line and cultured it in different glucose concentrations to analyze GLUT expression using Western blotting and flow cytometry.
- The study found that GLUT-1 levels increased in high glucose conditions, while GLUT-4 decreased, suggesting that these changes may contribute to the early signs of diabetic kidney disease.