Publications by authors named "Nikolaos Fatsis-Kavalopoulos"
Article Synopsis
- Antibiotic combinations are gaining importance for treating infections, but their clinical benefits are often unclear; the study analyzed interactions of various antibiotics against problematic Gram-negative bacteria.
- A total of 232 bacterial isolates were tested for growth inhibition with different antibiotic pairs, revealing that interactions can vary by isolate, resulting in common additive effects but rare synergistic ones.
- The research highlights the need for isolate-specific profiling in antibiotic combination therapy to avoid ineffective pairs and potentially identify beneficial synergistic interactions.
