Publications by authors named "Nikolaj S Winther"

Article Synopsis
  • Revision total hip arthroplasty (rTHA) is complex, particularly with significant bone loss affecting implant stability, and this study focused on evaluating outcomes using an uncemented modular implant design in 100 patients.
  • Out of the 101 hips analyzed, 51 had lower-grade bone defects (Paprosky types I-II) and 50 were more severe (types III-IV), with a follow-up averaging 5.8 years, assessing implant survival and clinical outcomes using various scoring measures.
  • The findings revealed a high 5-year implant survival rate of 95%, with successful osseointegration in all hips and no significant subsidence; however, some complications occurred, including dislocations and fractures, but overall
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Aims: Pelvic discontinuity is a rare but increasingly common complication of total hip arthroplasty (THA). This single-centre study evaluated the performance of custom-made triflange acetabular components in acetabular reconstruction with pelvic discontinuity by determining: 1) revision and overall implant survival rates; 2) discontinuity healing rate; and 3) Harris Hip Score (HHS).

Methods: Retrospectively collected data of 38 patients (39 hips) with pelvic discontinuity treated with revision THA using a custom-made triflange acetabular component were analyzed.

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Background: Peri-acetabular osteotomy is the joint-preserving treatment of choice in young adults with hip dysplasia but is associated with intense pain and high opioid consumption postoperatively.

Objectives: To investigate whether 48 mg of pre-operative dexamethasone was superior to a standard dose of 8 mg on reducing pain in the immediate postoperative phase.

Design: A randomised, double-blind trial.

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Loss of bone stock as a response to the bone trauma, immobilization, and stress shielding related to joint replacement surgery increases the risk of fracture of the distal femur after total knee arthroplasty. Previous studies of uncemented femoral components have reported very high levels of bone loss in the distal femur. This study investigates the adaptive bone remodeling of the distal femur after uncemented total knee arthroplasty.

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Article Synopsis
  • Regenerex is a new porous titanium implant designed to mimic the characteristics of natural bone, and this study compared its effectiveness to a traditional porous plasma sprayed (PPS) implant after total knee arthroplasty.
  • Sixty-one patients underwent uncemented knee surgery and were randomly assigned to receive either Regenerex or PPS implants, with migration of the implants measured over 24 months using radiostereometric analysis.
  • Results showed that while both implants improved knee function over time, Regenerex had a lower migration rate in the later months compared to PPS, but overall performance was similar at the 24-month follow-up.
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