Publications by Nikolaj M Slynko

Publications by authors named "Nikolaj M Slynko"

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Comparative study of CYP2B induction in the liver of rats and mice by different compounds.

Vladimir O Pustylnyak Anton N Lebedev Lyudmila F Gulyaeva Vyacheslav V Lyakhovich Nikolaj M Slynko

Life Sci

January 2007

Male Wistar rats and C57BL mice were treated by phenobarbital (PB), 2,4,6-triphenyldioxane-1,3 (TPD) and 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP). The CYP2B specific activities (PROD and BROD) were determined in the animal livers. PB administration significantly increased levels of PROD- and BROD-activity in the rat and mouse livers, whereas TPD induced CYP2B activities only in rat liver and TCPOBOP--only in mouse liver.

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