Publications by authors named "Nikolai Goncharov"

Article Synopsis
  • The traditional methods for measuring testosterone levels in blood are often inaccurate, particularly for women and children.
  • A new luminescence enzyme immunoassay (LIA) has been developed, showing high sensitivity for detecting low testosterone concentrations in both saliva and serum.
  • In healthy men, morning saliva testosterone levels were significantly higher than in men with androgen deficiency, and there was a strong correlation between free testosterone in saliva and calculated free testosterone in blood.
View Article and Find Full Text PDF

17Alpha-estradiol (1,3,5(10)-estratriene-3,17alpha-diol) together with a tracer dose of the tritium-labeled compound was administered orally and sublingually to male volunteers. The serum concentrations of 17alpha-estradiol (free and liberated by enzymatic hydrolysis) were quantified by GC/MS, and the serum total radioactivity and urinary radioactivity excretion were determined. After oral administration, 17alpha-estradiol was rapidly and intensively conjugated; only tiny quantities of the free steroid (<1% of total) appeared in serum.

View Article and Find Full Text PDF