Publications by authors named "Nikola Rakic"
Article Synopsis
- The study aimed to find links between military exposures and the risk of bladder cancer in veterans.
- A total of 25 studies involving over 4.3 million patients were reviewed, focusing on specific military agents that could contribute to cancer risk.
- Results indicated significant bladder cancer risks associated with Agent Orange and depleted uranium, highlighting the need for better screening and prevention protocols for veterans.
Background: Estimation of life expectancy (LE) is important for the relative benefit of prostate specific antigen (PSA) screening. Limited data exists regarding screening for Black men with extended LE. The aim of the current study was to assess temporal trends in screening in United States (US) Black men with limited vs.
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- Lymph-vascular invasion (LVI) is a serious concern for patients with kidney cancer, but its effect on survival isn't well understood.
- The study looked at almost 96,000 kidney cancer patients to find out if LVI affects how long they live after surgery.
- Results showed that patients with LVI survived less time overall compared to those without it, suggesting LVI is an important factor to consider when treating kidney cancer.
Unlabelled: Co-digestion implementation in wastewater treatment plants enhances biogas yield, so this research investigated the optimal ratio of biodegradable waste and sewage sludge. The increase in biogas production was investigated through batch tests using basic BMP equipment, while synergistic effects were evaluated by chemical oxygen demand (COD) balance. Analyses were performed in four volume basis ratios (3/1, 1/1, 1/3, 1/0) of primary sludge and food waste with added low food waste: 3.
View Article and Find Full Text PDFRisk-Based Assessment Of the Impact Of Intravesical Therapy on Recurrence-Free Survival Rate Following Resection of Suspected Low-grade, Non-muscle-invasive Bladder Cancer (NMIBC): A Southwest Oncology Groups (SWOG) S0337 Posthoc Analysis.
Clin Genitourin Cancer
December 2022
Background: Nonmuscle invasive bladder cancer (NMIBC) has an elevated risk of recurrence, and immediate postresection intravesical instillation of chemotherapy (IVC) significantly reduces the risk of recurrence. Questions remain about which subpopulation may maximally benefit from IVC. Our aim was to develop risk groups based on recurrence risk in NMIBC, and then evaluate the impact of a single, postoperative instillation of IVC on the subsequent risk of recurrence for each risk group.
View Article and Find Full Text PDFBackground: The detrimental impact of lymphovascular invasion (LVI) in prostate cancer (PCa) on biochemical recurrence has been described; the impact of LVI on overall survival (OS) remains unclear. This investigation sought to evaluate the impact of LVI on OS in patients with PCa.
Methods: We examined men with nonmetastatic PCa treated with radical prostatectomy between 2010 and 2015.
Objective: To assess the prognostic ability of lymphovascular invasion (LVI) as a predictor of overall survival (OS).
Materials And Methods: We included 126,682 prostate cancer (CaP) cM0 patients who underwent radical prostatectomy with lymph node dissection between 2010 and 2015, within the National Cancer Database. Patients who received androgen deprivation therapy were included.
Purpose: Ductal adenocarcinoma is considered a rare histological variant of prostate adenocarcinoma (PCa). Given the rarity of this subtype, optimal treatment strategies for men with nonmetastatic ductal PCa is largely unknown. We aimed to describe the impact of surgery, radiotherapy, systemic therapy, and observation on overall survival (OS) in men with nonmetastatic ductal PCa.
View Article and Find Full Text PDFObjective: To examine the utilization of adjuvant radiotherapy (aRT) in contemporary prostate cancer patients with adverse pathological features at radical prostatectomy (RP).
Methods: We identified 189,240 patients with adverse features at RP (positive margin, stage ≥pT3a, and/or pN1 disease), from 2004 to 2015, within the National Cancer Database, and validated our findings within Surveillance, Epidemiology, and End Results (SEER) program. We examined the utilization of patients with aRT with adverse features at RP and patients with very aggressive disease (at least 2 of the following: ≥pT3b, pathological Gleason 8-10, and pN1).