[Morphological characteristics of actinomycotic dacryocanaliculitis].

The paper presents the results of pathohistological studies of the contents of the lacrimal canaliculi and the fragments of their walls, obtained at canaliculotomy in 25 patients. This permitted 14 cases of actinomycotic dacryocanaliculitis to be identified as drusens of the ray fungus Actinomyces israelii had been found. The reactive structural changes found in the wall of the lacrimal canaliculi due to the presence of fungal infection and foreign bodies in their lumen are described.

[Involvement of lacrimal organs in Wegener's granulomatosis].

Wegener's granulomatosis (WG) is a primary systemic vasculitis characterized by the development of granulomatous inflammation and necrotizing vasculitis of small- and middle-sized vessels. The clinical symptoms of the involvement of lacrimal organs in WG are of no specificity. Lacrimal tract lesion is encountered in prolonged Wegener's granulomatosis.

[Morphological features of the mucosa of the nasal cavity and lacrimal sac in lacrimal passage obstruction].

A comprehensive morphological study of the mucosa of the nasal cavity and lacrimal sac was conducted, by using 160 biopsy specimens taken from 44 patients at endoscopic endonasal dacryocystorhinostomy. In all cases, different areas of the nasal cavity exhibited abnormal changes that were generalized and appeared as inflammatory, dystrophic, and sclerotic processes.

[Lactase deficiency in children of the first year of life].

In the article the new aspects of development of lactose malabsorbtion at children of the first year of life are resulted. The oligosaccharides and glycosydases of female milk have the certain importance in development of this pathology.

[Medical and biological assessment of genetically modified corn line MON 810 resistant to European corn borer and line GA 21 resistant to glyphosate: a chemical study].

Chemical analysis of genetically modified corns MON 810 resistance to European corn borer and GA 21 tolerance to glyphosphate was performed. Results of these studies showed that there is no difference between genetically modified and conventional corn products.

[Effect of fructose-containing beverages on glycemic parameters in patients with type II diabetes mellitus].

The dynamics of glycemia after meal in 21 patients with type II diabetes under the influence of drinks with fructose or sugar and enriched with soluble fibres was investigated. To estimate glycemia after meal in first stage of investigation the test-meals with 50 g carbohydrates (cocktails of juices "Multivitamin" with fructose and sugar, or bread) were used. In second stage, carbohydrates "Peach nectar with fructose" and cocktail of juices "Multivitamin with fructose" were used.

[Intubation granulomas of the lacrimal ducts in patients with silicone implants].

The results of 315 endonasal operations on the lacrimal duct with long intubation are analyzed. The most incident complication of long intubation of the lacrimal duct is formation of intubation granulomas, which are most often localized in the inferior lacrimal canaliculus; their etiology is sometimes allergic--they form as a response of adjacent tissues to the material of the intubation tube, and the findings of our recent histological study prove it. The diagnosis of intubation granulomas is easy in the majority of cases.

[The status of the Moscow pathoanatomical service and the outlook for its improvement].

The paper concerns the problems facing pathologic anatomy service in Moscow. It is stated that the service needs reorganization. The advances in methodology, staffing, continued training, salary system, connections with other services should be accomplished.

[Lactose digestion and absorption in the jejunum of man: studies using the regional perfusion method].

Continuous jejunal perfusion with 0.1, 1 and 10% lactose solutions was made in 9 patients with good milk tolerance and 25 patients with secondary hypolactasia. In normal tolerance lactose is assimilated in amounts of 30-60% along the 30 cm of the jejunal length.

[Syndrome of the superior oblique muscle rigidity: clinico-anatomical aspects and results of treatment of 8 patients].

Tenectomy of the superior oblique muscle resulted in complete disappearance of Brown's syndrome in 7 out of 8 children operated on. In view of this, it can be a method of choice in treatment of the syndrome. There was the first clinical case of an additional abnormal attachment of the superior oblique muscle tendon to the sclera.

[Surgical correction of astigmatism using kerato-resection methods].

The authors analyze the results of surgical correction of hypermetropic and mixed astigmatism, carried out by two methods: clinoid resection of the cornea and clinoid resection of the cornea with tangent autoclinoplasty (i. e. implantation of the resected site to the tangent incision in strongly refracting meridian).

[Our initial experience with the surgical correction of astigmatism by sectorial keratorrhaphy].

The authors analyze the first experience with surgical correction of corneal astigmatism by sectorial keratorrhaphy (SKR). The operation consists in sewing an intralamellar nylon (9.00) suture perpendicular to poorly refracting meridian of the cornea.

[Effects of sodium oxybutyrate on the level of catecholamines and serotonin and monoamine oxidase activity in patients with alcoholism].

Sodium salt of gamma-hydroxybutyric acid (Na-GHB) was administered to 37 drug-free alcoholic men in placebo controlled study. The psychotropic effect was evaluated using psychometric scale of 4 ranges. Changes in plasma levels of epinephrine, norepinephrine, dopamine, serotonin and platelet MAO-B activity were assessed.

[Morphological research on different ways of joining the rectus muscles of the eye].

The paper analyses results of comparative clinico-morphological studies of two methods for ocular rectus muscles a sutural and a loop methods used in 8 rabbits (16 eyes). Histologic examination of specimens of eye made 4-6 months after surgical intervention has shown that a loop method provides preservation of the structure of muscular tissue to a much greater degree than a sutural method. The results obtained allow to consider the loop method to be a method of choice for the usage in clinical practice as being less traumatic.

[Changes in lipid metabolism and renewal of sialic acids in the composition of glycoproteins of adipose tissue during carbohydrate loading].

With an increase in content of sugar in a diet from 10% to 50% of the caloric value the rate of synthesis and accumulation of lipids were increased in perinephric adipose tissue of rats exhibiting the maximal values at 30% content of sugar in rations. Under these conditions content of insulin was decreased in blood and half-life of sialic acids was decreased in glycoproteins of adipose tissue. Interrelationship between sensitivity of the adipose tissue receptors to insulin and the half-life of sialic acids was considered.

[Effect of fructose on the hexosamine turnover in the rat crystalline lens].

Rats were given isocaloric rations containing starch (control) and varying amounts of fructose as carbohydrates. Hexosamines were isolated from the lens, glycoproteins--from the blood serum, and their turnover was studied. A drastic deceleration of hexosamine turnover in the lens was observed at high-fructose diets (20 and 40% of fuel value), while glycoprotein turnover in the blood plasma was not changed as compared to the control, glucose-6-phosphate dehydrogenase in red blood cells was decreased, insulin level was lowered, and glucose level in the blood serum rose insignificantly.

[Turnover of hexosamines in the lens and glycoproteins in the blood of rats given a xylose-containing diet].

To elucidate the action of xylose admixtures during the biotechnological production of monosaccharides, rats were given rations containing xylose that comprised 2.10 and 20% of the total amount of carbohydrates. Hexosamines of the lens and general blood globulin fraction were isolated and their turnover was investigated.

[Phospholipid turnover of the liver subcellular fractions in rats receiving diets with a varying protein content].

Turnover of liver mitochondrial and microsomal phospholipids was studied in rats kept on isocaloric diets containing 4.5, 6, 9, 18% protein (controls) and 36%. Turnover rate and half-life period of mitochondrial and microsomal phospholipids were determined from degradation of membrane fractions of phospholipids labeled with 14C-palmitic acid.

[Turnover of the amino sugars of erythrocyte and thrombocyte glycoproteins in rats maintained on different carbohydrate diets].

The turnover of erythrocyte and platelet glycoprotein amino sugars in rats fed carbohydrates has been studied. Partial replacement of starch by sucrose results in an almost 3-fold increase in the half-life of erythrocyte glycoprotein amino sugars and in a 2-fold increase in that of platelets as early as 14 days after keeping the animals on carbohydrates. It is concluded that study of dynamic parameters of cell amino sugars can be used for evaluation of the role played by food in metabolic and adaptive reactions both in experimental animals and man.