Publications by authors named "Niklas Sandler Topelius"
The exploration of three-dimensional (3D) printing inspired technologies in pharmaceutical compounding reveals a promising frontier in personalized medicine manufacture. This study focuses on the development of clopidogrel bisulphate tablets, with doses ranging from 2 mg to 20 mg per tablet, suitable for pediatric use. The study explored a semi-solid extrusion-based deposition technology already being used in compounding pharmacies across several European locations.
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- Pharmacy compounding is evolving with new technologies that address traditional challenges like dosage accuracy and contamination by utilizing automated processes, enhancing quality control.
- A multi-site study involving over 30 hospitals and pharmacies across eight European countries tested a novel automated approach to create customized non-sterile propranolol hydrochloride tablets, significantly improving dosing accuracy from 90% to 100%.
- The research indicates that incorporating automation and advanced quality control measures can transform pharmacy compounding, paving the way for more efficient and reliable personalized medicine production.
Overcoming the health threatening consequences of staphylococcal infections and their negative socio-economic effects have become a priority in the medical, pharmaceutical, food and many other sectors globally. Staphylococcal infections are a big challenge for a global health care, since they are difficult to be diagnosed and treated. Therefore, the development of new medicinal products of plant-origin is timely and important, because bacteria have a limited ability to develop resistance to such products.
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