[Accidental falls in the elderly].

Falls in the elderly are common with consecutive high mortality and morbidity. Recent consecutive data focus on identification and therapy of intrinsic risk factors. Sarcopenia, imbalance and gait disorders represent the major risk factors.

Decrease in VEGF expression induces intussusceptive vascular pruning.

Objective: The concept of vascular pruning, the "cuting-off" of vessels, is gaining importance due to expansion of angio-modulating therapies. The proangiogenic effects of vascular endothelial growth factor (VEGF) are broadly described, but the mechanisms of structural alterations by its downregulation are not known.

Methods And Results: VEGF(165)-releasing hydrogels were applied onto the chick chorioallantoic membrane on embryonic day 10.