Publications by authors named "Nikki Bakker"
Article Synopsis
- Obesity leads to low-grade inflammation, increasing the risk of insulin resistance, with leptin being a key player by regulating food intake and being elevated in obese individuals.
- Leptin enhances macrophage responses to inflammation, promoting cytokine production and changes in mitochondrial function, thereby intensifying the inflammatory response.
- Intervening in leptin signaling pathways may offer new strategies for treating obesity-related inflammation and improving insulin resistance.
Aims: Self-efficacy may predict performance following life-support training but may be negatively influenced by experiences during training. To investigate both this and the use of self-efficacy in self-assessment we investigated the relationship between self-efficacy and measured performance during a simulated resuscitation, and the effect of death of a simulated patient on self-efficacy.
Materials And Methods: Consultant and trainee paediatricians and anaesthesiologists scored their self-efficacy for paediatric resuscitation skills before taking an unannounced simulated resuscitation test and objective structured clinical examination (OSCE)-tests of chest compressions and bag- and mask-ventilation.