Publications by authors named "Nikita Pedyash"

Article Synopsis
  • The study looked at how well patients recover their language skills after having brain surgery for a type of tumor on the left side of the brain.
  • Researchers tested 59 patients' language abilities before surgery, right after, and several months later to see how they changed.
  • They found that while some patients didn't recover well, better immediate language mapping during surgery helped with recovery, especially in areas like understanding sentences and using verbs.
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High-frequency oscillations (HFO) are a promising biomarker for the identification of epileptogenic tissue. While HFO rates have been shown to predict seizure outcome, it is not yet clear whether their morphological features might improve this prediction. We validated HFO rates against seizure outcome and delineated the distribution of HFO morphological features.

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Unlike stroke, neurosurgical removal of left-hemisphere gliomas acts upon a reorganized language network and involves brain areas rarely damaged by stroke. We addressed whether this causes the profiles of neurosurgery- and stroke-induced language impairments to be distinct. K-means clustering of language assessment data (neurosurgery cohort: N = 88, stroke cohort: N = 95) identified similar profiles in both cohorts.

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The left frontal aslant tract (FAT) has been proposed to be relevant for language, and specifically for spontaneous speech fluency. However, there is missing causal evidence that stimulation of the FAT affects spontaneous speech, and not language production in general. We present a series of 12 neurosurgical cases with awake language mapping of the cortex near the left FAT.

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