Publications by authors named "Nikita Lad"

This brief provides data for policy changes on the intersection of polluting industrial facilities, marginalized communities, and the dearth of air-quality monitors in those communities of South Chicago. The allocation of air-quality monitors is determined by the Illinois Environmental Protection Agency (IEPA). Our data demonstrate that the air quality and subsequent health of Chicago's marginalized communities are chronically threatened by the expansion of polluting industries coupled with inadequate air-quality monitoring.

View Article and Find Full Text PDF

Low-grade inflammation is often an underlying cause of several chronic diseases such as asthma, obesity, cardiovascular disease, and type 2 diabetes mellitus (T2DM). Defining the mediators of such chronic low-grade inflammation often appears dependent on which disease is being investigated. However, downstream systemic inflammatory cytokine responses in these diseases often overlap, noting there is no doubt more than one factor at play to heighten the inflammatory response.

View Article and Find Full Text PDF
Article Synopsis
  • Brain tumors, particularly glioblastomas, are the leading cause of cancer-related deaths in individuals under 40, with a very low survival rate.
  • Researchers conducted a human kinome siRNA screen to find new drug targets that could enhance the effectiveness of temozolomide (TMZ), the standard treatment for glioblastoma.
  • They discovered that ERK5 plays a crucial role in helping glioblastoma cells survive TMZ treatment, and higher ERK5 levels in tumors are linked to more aggressive cancers and lower patient survival rates, suggesting that targeting ERK5 could improve treatment outcomes.
View Article and Find Full Text PDF