Efficacy and Safety of Anti-malarial Drugs (Chloroquine and Hydroxy-Chloroquine) in Treatment of COVID-19 Infection: A Systematic Review and Meta-Analysis.

Anti-malarial drugs inhibit coronaviruses . Few published studies have evaluated the safety and efficacy of these drugs in the treatment of COVID-19 infection. This is a systematic review and meta-analysis of clinical trials and observational studies.

Palliative drug treatments for breathlessness in cystic fibrosis.

Background: Cystic fibrosis is a life-limiting autosomal recessive genetic illness. A feeling of shortness of breath is common in cystic fibrosis, especially as the disease progresses. Reversing the underlying cause is the priority when treating breathlessness (dyspnoea), but when it is not feasible, palliation (easing) becomes the primary goal to improve an individual's quality of life.