Publications by authors named "Nikita H Seth"

Article Synopsis
  • Longitudinal extensive transverse myelitis (LETM) is a rare neurological condition characterized by inflammation in the spinal cord affecting three or more vertebrae, leading to severe symptoms like weakness and sensory issues.
  • LETM can be either idiopathic or linked to autoimmune diseases such as Multiple Sclerosis and Neuromyelitis Optica, and its diagnosis involves MRI imaging of the spine.
  • A case study of a 62-year-old male showed improvements in mobility and functional independence after a combination of corticosteroids, IVIG, plasma exchange, and physical therapy following his diagnosis of LETM.
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  • * The patient presented drowsy and weak with a Glasgow Coma Scale score of 11, showing signs such as tachycardia and increased muscle tone; diagnostic tests confirmed NMS with elevated urea, creatinine, and creatine phosphokinase levels.
  • * Treatment involved stopping clozapine and starting bromocriptine, alongside vital physiotherapy, which improved the patient's mobility and mental status significantly over two weeks, illustrating
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Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse reaction to many first- and second-line chemotherapy medications that can be debilitating, severe, and often dose-limiting. Treatment options for CIPN are limited. We report a case of a 52-year-old female patient with Stage II ovarian cancer who was hospitalised in the chemotherapy ward for a second round of chemotherapy.

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Infantile systemic hyalinosis (ISH) is a very rare autosomal recessive disorder, which is characterized by a systemic build-up of hyaline material that causes extensive tissue destruction and functional impairment. The signs of this debilitating illness, which can involve organs, skin anomalies, and joint contractures, frequently appear in infancy. The paucity of available research on ISH emphasizes the need for all-encompassing management approaches to address the wide range of symptoms and enhance the overall quality of life for impacted babies.

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  • Guillain-Barré syndrome (GBS) involves immune-mediated nerve damage, with acute motor axonal neuropathy (AMAN) highlighting motor issues and nerve degeneration, notably in a 29-year-old male patient.
  • Diagnosis included nerve conduction velocity testing after gastrointestinal symptoms led to muscle weakness, followed by intravenous immunoglobulin therapy.
  • The physiotherapy protocol, lasting eight weeks, focused on enhancing muscle strength and functional independence through tailored exercises and included virtual reality training to boost balance and limb function, resulting in notable patient improvements.
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Neurometabolic disorders encompass a diverse group of conditions characterized by inborn errors of metabolism, affecting various aspects of neurological function. This case report focuses on an 11-year-old male child with a neurometabolic disorder who presents with walking difficulties, speech impairment, and neurological symptoms. The background emphasizes the heterogeneity of neurometabolic disorders, their genetic and clinical complexity, and the need for tailored interventions to address specific manifestations.

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Introduction Nomophobia is an emerging phobia resulting from people's excessive interaction with mobile phones. This phobia is rapidly increasing due to significant technological innovations and widespread acceptance and usage of mobile phones worldwide. Nomophobia is often associated with complications such as panic attacks, irritability, and anxiety.

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Leukoencephalopathy (LE), characterized by structural changes affecting cerebral white matter, presents a complex clinical picture with diverse etiologies. This case report details the presentation, clinical findings, and physiotherapy management of a 32-year-old female with colony-stimulating factor 1 receptor (CSF1R)-related leukoencephalopathy and a history of diabetes and hypertension. She suddenly stopped her medications, which led to the worsening of her condition.

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Down syndrome (DS) is a genetic condition developing from a supplementary chromosome 21, referred to as trisomy 21. It ranks among the most prevalent developmental disabilities. People with DS often live inactive lifestyles, not meeting the weekly physical activity guidelines.

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A stroke is a medical emergency that requires rapid treatment. Early intervention can help prevent brain damage and other negative consequences. An ischemic stroke occurs when a blood clot blocks or narrows a blood artery leading to the brain.

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Hirschsprung disease (HD) is characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of the hindgut. Here, we report a case of an eight-year-old male child who had abdominal distension with a history of repetitive gas passage and a complaint of stool passage. In February 2023, the patient was diagnosed with Hirshsprung disease, for which a left-side colostomy was done.

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Persistent pulmonary hypertension of the newborn (PPHN) is a condition that can be fatal, marked by increased pulmonary vascular resistance that causes blood to shunt from the right to the left. Six infants that present with PPHN due to labile hypoxemia and related cyanosis are examined in this case series. Clinical manifestations, such as premature deliveries, maternal problems, and different reactions to early therapies, are revealed by perinatal and postnatal histories.

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  • Korsakoff syndrome and Wernicke's encephalopathy (WE) are neurological conditions usually linked to chronic alcohol consumption, resulting in cognitive and physical deficits.
  • A tailored rehabilitation protocol including cognitive and physical interventions, along with thiamine supplementation, showed significant improvement in a 49-year-old male patient's cognitive function and independence.
  • The case study highlights the need for personalized rehabilitation strategies that integrate physiotherapy with cognitive care to enhance overall quality of life for patients with WKS.
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There is a complex link between tuberculous meningitis (TBM) and aphasia, in which a language impairment is caused by an injury to the cortical language centre. The parts of the brain that function for speech and language production are the Wernicke's, Broca's, and arcuate fasciculus regions. This case report mainly highlights the neurological consequences of TBM, and how it affects language and speech functioning.

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  • Stroke is increasingly common in developing countries and often leads to long-term physical inactivity and deconditioning after an ischemic event.
  • A case study details an 86-year-old woman who suffered an external capsule ischemic stroke, experienced severe weakness, and was treated with intensive care followed by tailored physical therapy.
  • The two-week physiotherapy intervention focused on gait training, muscle strengthening, and balance, demonstrating significant benefits and highlighting the importance of early, targeted rehabilitation for stroke recovery.
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This case report presents a 54-year-old male with a history of type-2 diabetes mellitus who experienced sudden unconsciousness and vomiting, leading to aspiration and subsequent diagnosis of a hemorrhagic stroke. The patient underwent an immediate decompressive craniotomy, revealing a sizable intraparenchymal hematoma in the right basal ganglia and corona radiata. Postoperatively, the patient exhibited left-sided weakness, hyporeflexia, and cognitive impairment.

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A head injury or cerebrovascular illness may be the cause of acute intracranial hemorrhage. Making a precise diagnosis is challenging since diagnostic imaging might be challenging in both situations. In this case report, an aneurysmal rupture related head injury resulted in an acute subdural hematoma (SHD) after the patient lost consciousness.

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Meningitis caused by bacteria, which is an inflammation of the meninges affecting the pia, arachnoid, and subarachnoid space, is still one of the leading causes of death and morbidity in infants and young children. , group B streptococcus (GBS), type B (Hib), , and have been found to be the most frequent causative agents. Infants and children can have modest, fluctuating, non-specific, or even absent clinical signs of bacterial meningitis.

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  • Cancer treatment can lead to chemotherapy-induced peripheral neuropathy (CIPN), which currently lacks effective prevention and treatment methods.
  • This study reviewed randomized controlled trials (RCTs) to assess how effective physical therapy is for patients experiencing CIPN.
  • The findings suggest that while physical therapy can improve patients' quality of life, the results are limited by diverse treatment methods and small study sizes, highlighting the need for further research.
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We report a rare case of a 32-year-old male diagnosed with a mass of intussusception in the right lumbar region. Adult intussusception has a prevalence of less than 5%. Among all cases of intestinal obstructions, adult intussusception is found to be only 1-3%.

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The standard treatment for multiple levels of cervical prolapsed intervertebral disk (PIVD) is anterior cervical decompression and fusion. Although it is associated with positive outcomes, it is also fraught with complications. In this report, we present an unusual postoperative case of a 58-year-old male who underwent anterior decompression and cervical fusion at two levels - C4-C5 and C5-C6 - for traumatic PIVD and developed a postoperative complication of unilateral C5 motor palsy, making it difficult for the patient to elevate the shoulder.

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Mental health has suffered considerably as a result of advancing time and technological developments. Poor quality of sleep affects people of all ages, and non-pharmacological remedies are becoming increasingly important. Nearly 60% of all undergraduate students are reported to have a poor quality of sleep, with 7.

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