Publications by authors named "Nikita Goel"
Article Synopsis
- A 72-year-old woman with pre-existing health issues underwent an ERCP to remove bile duct stones but faced complications including abdominal pain and jaundice post-surgery.
- During the ERCP, she experienced a drop in oxygen saturation and arrhythmia, leading to a diagnosis of gas embolism confirmed by imaging, revealing air bubbles in her heart.
- Despite several emergency interventions, her condition worsened, and due to financial constraints, she was discharged against medical advice, highlighting the rarity and management difficulties of ERCP-related air embolism.
Background: Multimorbidity among older adults is a growing concern in India. Multimorbidity is defined as the coexistence of two or more chronic health conditions in an individual. Primary studies have been conducted on risk factors of multimorbidity in India, but no systematic review has been conducted on this topic.
View Article and Find Full Text PDFPurpose: To describe the subretinal hyporeflective globule in cases of central serous chorioretinopathy (CSC).
Methods: A retrospective analysis of consecutive cases of CSC presenting to a tertiary eye care center in eastern India was conducted. Subretinal hyporeflective globules were identified as small globular lesions below the external limiting membrane/ellipsoid zone, but above the RPE layer.
Purpose: To discuss the features of an artifact on optical coherence tomography angiography (OCTA), termed "pupil vignetting artifact," and describe how it may masquerade as true chorioretinal pathology.
Design: This was a retrospective, observational case series.
Methods: The authors studied 12 eyes at a vitreoretinal clinic in Eastern India, reviewing a dark shadow such as an artifact on OCTA images.
Predictive Modeling Of Alzheimer's Disease Prognosis Using Anatomical & Diffusion MRI.
Annu Int Conf IEEE Eng Med Biol Soc
July 2023
Mild cognitive impairment (MCI) is an intermediate stage between healthy aging and Alzheimer's disease (AD), and AD is a progressive neurodegenerative disorder that affects around 50 million people worldwide. As new AD treatments begin to be developed, one key goal of AD research is to predict which individuals with MCI are most likely to progress to AD over a given interval (such as 2 years); if successful, these individuals could be preferentially enrolled in drug trials that aim to slow AD progression. Here we benchmarked a range of MCI-to-AD predictive models including linear regressions, support vector machines, and random forests, using predictors from anatomical and diffusion-weighted brain MRI, age, sex, APOE genotype and standardized clinical scores.
View Article and Find Full Text PDFPurpose: Cystoid macular degeneration (CMD) is a feature of chronic central serous chorioretinopathy (CSCR). Present study intended to analyze the clinical presentation, risk factors, choroidal features, and outcome of CMD in CSCR.
Methods: This was a retrospective, record-based descriptive study, which included chronic CSCR eyes with CMD.
Article Synopsis
- * NADH serves as a key electron donor, interacting with two types of NADH dehydrogenases: Type I, which helps generate proton motive force, and Type II, which is important for NAD+ turnover.
- * By evolving a mutant without type II NADH dehydrogenase, researchers found that adjusting the TCA cycle flux can help mitigate growth issues, offering insights into bacterial energy metabolism adaptations.
Purpose: To analyze the imaging characteristics and the clinical course of patients showing concomitant paracentral acute middle maculopathy (PAMM) and acute macular neuroretinopathy (AMN) post-blunt trauma.
Methods: PAMM and AMN lesions post-blunt trauma diagnosed on enhanced depth imaging optical coherence tomography (EDI-OCT) were recruited for the study.
Results: : Thirteen eyes of 13 individuals with a history of blunt trauma were included in the study, of whom 11 (85%) were males.
Since December 2019, coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has become a global pandemic. There has been a resurgence in complications involving various organs in patients recovered from COVID-19, and endophthalmitis is one of them. Endophthalmitis-an inflammation of intraocular tissues leading to loss of vision or even loss of eye-has been a rare occurrence in the past, but has been on the rise in the post-COVID-19 times.
View Article and Find Full Text PDFPrevalence of Flu-like Symptoms and COVID-19 in Healthcare Workers from India.
J Assoc Physicians India
July 2020
Background: The current COVID-19 pandemic is unprecedented. As the numbers expand exponentially, a paucity of data regarding health care workers (HCWs), who are at the forefront of this disaster, exists. Hence we decided to conduct a study amongst the HCWs to determine the prevalence and risk factor stratification.
View Article and Find Full Text PDFContext: Integrative medicine (IM) is a rapidly growing field whose providers report clinical success in treating significant stress, chronic pain, and depressive and anxiety symptoms. While IM therapies have demonstrated efficacy for numerous medical conditions, IM for psychological symptoms has been slower to gain recognition in the medical community.
Objective And Design: This large, cross-sectional study is the first of its kind to document the psychosocial profiles of 4182 patients at 9 IM clinics that form the BraveNet Practice-Based Research Network (PBRN).
Background: Periorificial dermatitis (POD) is a rosacea-like papulopustular facial eruption most commonly reported in young adult women. Although POD has been reported in children as young as 6 months of age, there are limited data on the diagnosis and management of POD in pediatric cases.
Methods: All children diagnosed with POD at the Dermatology Clinic at the University of North Carolina at Chapel Hill between June 2002 and March 2014 were included in the current study.