Publications by authors named "Nikita Aware"
Article Synopsis
- Glioblastoma (GBM) is a lethal brain cancer that is currently incurable, but CAR T cells targeting multiple antigens show potential for better treatment.
- Researchers developed a trivalent CAR T-cell product that targets three glioma antigens (HER2, IL13Rα2, and EphA2) to address variability in antigen expression among patients.
- Findings indicate that this UCAR T-cell approach effectively captures tumor cells, enhances cytotoxicity, and improves survival in preclinical models by overcoming antigenic diversity in GBM.
