Publications by authors named "Nikita A Savin"
Electrospun Composites of Chitosan with Cerium Oxide Nanoparticles for Wound Healing Applications: Characterization and Biocompatibility Evaluation In Vitro and In Vivo.
Polymers (Basel)
June 2024
Article Synopsis
- * The addition of CeONPs reduces fiber diameter and increases swelling and mechanical strength in the mats, while maintaining similar cell adhesion and compatibility with mesenchymal stem cells compared to standard CS-PEO mats.
- * In vivo studies showed that CS-PEO-CeONP mats had no acute toxicity or adverse inflammation and displayed slower biodegradation, indicating potential for improved healing and tissue integration over time.
Novel derivatives of Mycosidine (3,5-substituted thiazolidine-2,4-diones) are synthesized by Knoevenagel condensation and reactions of thiazolidines with chloroformates or halo-acetic acid esters. Furthermore, 5-Arylidene-2,4-thiazolidinediones and their 2-thioxo analogs containing halogen and hydroxy groups or di(benzyloxy) substituents in 5-benzylidene moiety are tested for antifungal activity in vitro. Some of the synthesized compounds exhibit high antifungal activity, both fungistatic and fungicidal, and lead to morphological changes in the yeast cell wall.
View Article and Find Full Text PDFMechanical properties of living cells determined by cytoskeletal elements play a crucial role in a wide range of biological functions. However, low-stress mapping of mechanical properties with nanoscale resolution but with a minimal effect on the fragile structure of cells remains difficult. Scanning Ion-Conductance Microscopy (SICM) for quantitative nanomechanical mapping (QNM) is based on intrinsic force interactions between nanopipettes and samples and has been previously suggested as a promising alternative to conventional techniques.
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