Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study.

Background: Results of several studies published since 1999 suggest that primary hyperaldosteronism (also known as Conn's syndrome) affects more than 10% of people with hypertension; however, such a high prevalence has also been disputed. Experts generally agree that resistant hypertension has the highest prevalence of primary hyperaldosteronism, on the basis of small studies. We aimed to assess the prevalence of primary hyperaldosteronism in a large group of patients with resistant hypertension.

Hypertension associated with rhabdomyolysis.

Primary aldosteronism accompanied by hypokalemia is a cause of secondary hypertension. Diagnosis of primary aldosteronism has increased dramatically in recent years with the wider availability of aldosterone and plasma renin activity measurements. The authors present the case of a patient with resistant hypertension and severe hypokalemia that evaded diagnosis until complications from hypokalemia occurred.