Skeletal Muscle Involvement in Wilson Disease: Clinical and Magnetic Resonance Imaging (MRI) Observations in 2 Families.

Objective: Skeletal muscle involvement in Wilson disease is rare. Calf muscle pain might be attributed as growing pain in children. We report calf muscle involvement in Wilson disease and describe the magnetic resonance imaging (MRI) findings of leg, differential diagnosis with literature review.

Skull base and calvarial tuberculosis presenting as chronic meningitis.

Calvarial tuberculosis is very rare accounting for 0.2-1.3% of skeletal tuberculosis.

Evaluation of the signal quality of wrist-based photoplethysmography.

Objective: Wearable devices with embedded photoplethysmography (PPG) sensors enable continuous monitoring of cardiovascular activity, allowing for the detection cardiovascular problems, such as arrhythmias. However, the quality of wrist-based PPG is highly variable, and is subject to artifacts from motion and other interferences. The goal of this paper is to evaluate the signal quality obtained from wrist-based PPG when used in an ambulatory setting.