Publications by authors named "Nikhil K Mandava"

Purpose Of Review: The increasing prevalence of diabetic macular edema (DME) necessitates an updated review of treatment modalities. While the shift from laser to anti-vascular endothelial growth factor (anti-VEGF) therapy has transformed patient outcomes, benefits of these agents are not fully realized in real-world implementation relative to the setting of controlled clinical trials. This review outlines the evolution of intravitreal anti-VEGF treatment extension protocols for DME that reflect efforts to address treatment adherence challenges while optimizing visual outcomes.

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Background: Hyperglycemia is a known risk factor for tendon degeneration due to oxidative stresses from production of advanced glycosylation end products. In patients with diabetes mellitus (DM), analysis of glycated hemoglobin (HbA) provides a 3-month window into a patient's glucose control. No guidelines exist for ideal preoperative HbA and glucose control prior to arthroscopic rotator cuff repair.

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Article Synopsis
  • A recent study looked at how many pain pills people really need after shoulder surgery and found that many patients might not need a lot of them.
  • The research involved 63 patients using different pain management methods, and they kept track of how much pain they felt and how many pills they took.
  • Most patients used only 15 or fewer pain pills after surgery, and some didn't need any at all, showing that better pain management techniques can help people use less medication.
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Purpose: To prospectively observe opioid consumption in patients undergoing knee arthroscopy and to create an evidence-based guideline for opioid prescription.

Methods: This prospective multicenter observational study enrolled patients undergoing outpatient knee arthroscopy for meniscal repair, meniscectomy, or chondroplasty. Patients were provided with a pain journal to record postoperative opioid consumption, Numeric Pain Rating Scale (NPRS) pain scores, and Likert scale satisfaction scores for 1 week postoperatively.

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Article Synopsis
  • Doctors are trying to find better ways to manage pain after shoulder surgery, instead of just giving out lots of strong painkillers like opioids, which can lead to problems later on.
  • In a study with 100 patients, they looked at how many pain pills people needed after their surgery and tested a new type of pain relief to see if it worked better.
  • Results showed that many patients needed fewer pills than expected, and those who got the new pain relief felt less pain and used fewer opioids than those who got the standard treatment.
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Purpose: To quantify the use of 5 mg oxycodone by patients who have undergone knee arthroscopy.

Methods: Patients who underwent knee arthroscopy at 2 institutions between May 2018 and May 2019 were identified retrospectively. Patients were called and queried about the following metrics: total postoperative opioid consumption, preoperative opioid consumption (defined as within 3 months of surgery), smoking status, and history of depression.

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Background: Arthroscopic rotator cuff repair (ARCR) provides excellent clinical outcomes but is often associated with significant postoperative pain. The use of intraoperative anesthesia in conjunction with multimodal pharmacologic strategies is a widely accepted approach for managing surgical pain and reducing opiate use. The purpose of this study was to determine whether using a combined field and suprascapular nerve block with liposomal bupivacaine (LB) in addition to an interscalene block would provide greater pain relief and a reduction in opiate consumption compared with an interscalene block alone.

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