An analysis of world media reporting of two recent large randomized prospective trials investigating screening for prostate cancer.

Objectives: •The publication of two large screening studies for prostate cancer (CaP), the Prostate Lung Colorectal Ovarian Cancer (PLCO) and the European Randomized Study of Screening for Prostate Cancer (ERSPC), has generated intense interest in medical and lay press not only as a result of their robust size, but also their opposing outcomes and differing methodologies, making interpretation controversial. •To characterize the world online media response to the studies by assessing reports for quality and message, as well as noting geographical differences.

Materials And Methods: •Major newspapers in North America, UK and Australia reporting online and Internet-only news organizations were analyzed for their reporting of CaP screening in response to the trials for a period of 6 months post-release.

Prostate-specific antigen test result interpretation when combined with risk factors for recommendation of biopsy: a survey of urologist's practice patterns.

Introduction: Recent data have suggested historical cutoff levels for prostate cancer (PC) screening using a prostate-specific antigen (PSA) level ≤ 4 ng/ml may no longer be appropriate with cancer detected at lower levels, particularly in younger men. Our aim was to conduct a contemporary survey of urologist's practice patterns toward PC detection, specifically focusing on factors determining the decision to recommend ultrasound-guided biopsy (TRUS-BX).

Methods: Three hundred and sixty active urologists from the Canadian Urological Association were requested to complete an online questionnaire focusing on scenarios of varying age, family history, ethnicity and PSA.

'Prostatic evasive anterior tumours': the role of magnetic resonance imaging.

Objective: To review our experience and delineate the role of magnetic resonance imaging (MRI) in identifying patients presenting with a raised prostate-specific antigen (PSA) level and clinical findings suggestive of anterior predominant tumours, which appear to be significant, particularly in those with a previous negative biopsy or low-volume disease undergoing active surveillance.

Patients And Methods: We retrospectively reviewed our database to identify patients with anteriorly predominant tumours on MRI whom had undergone prostate biopsy.

Results: In all, 31 patients with anterior predominant tumours on MRI also had a positive biopsy (14 on active surveillance and 17 with previous negative biopsies).