Publications by authors named "Nika Samadzadeh Tabrizi"

Purpose: Following esophagectomy, annually several thousand patients in the United States (US) reach a stable post-esophagectomy status. Such patients may require general anesthesia (GA) for elective procedures, but no generally accepted guidelines exist for the induction of GA in post-esophagectomy patients.

Methods: A national survey describing a post-esophagectomy patient was emailed to 23,524 attending anesthesiologists who were members of the American Society of Anesthesiologists.

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Background: Ferroptosis, a form of regulated cell death associated with iron-dependent lipid peroxidation, plays a role in cancer progression. However, the specific mechanisms of ferroptosis in lung adenocarcinoma (LUAD) bone metastasis (BM) remain unclear. Using bioinformatics analysis, this study sought to identify the ferroptosis-associated genes involved in BM in LUAD, thus providing potential novel targets for the treatment of BM in LUAD.

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Article Synopsis
  • * HALT is usually asymptomatic and found incidentally but can lead to more serious issues like valve deterioration or immobility.
  • * There is ongoing debate about the clinical significance, screening, and management of HALT in these patients, highlighting the need for further research on risk factors and treatment options.
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  • Tricuspid valve replacement (TVR) using mechanical valves shows better long-term survival rates and lower reoperation risks compared to tissue valves, based on a review of 21 studies involving 7,166 patients.
  • Patients with mechanical valves had a lower risk of death (HR 0.77) and gained an average of 2.2 more years of life (12.4 vs 10.2 years).
  • While there was no significant difference in reoperation risk within the first 7 years, mechanical valves showed a substantially lower reoperation risk after 7 years (HR 0.24).
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  • The study investigates the effectiveness of aortic versus non-aortic cannulation strategies in patients undergoing surgery for acute type A aortic dissections (ATAAD).
  • A systematic review of 23 studies revealed that both cannulation methods had comparable ten-year overall survival rates (61.1% for aortic and 58.4% for non-aortic).
  • No significant differences were found in key outcomes such as operative mortality, stroke, renal failure, or need for renal replacement therapy between the two methods, suggesting similar surgical outcomes.
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  • * A study reviewed the staging accuracy of 227 lung cancer patients at a tertiary institution, revealing that 80.9% of those with SMPLC were incorrectly staged, primarily by CT and PET-CT reports.
  • * The study highlights significant risks of mismanagement in SMPLC patients from flawed staging, urging improved awareness and accuracy in radiographic and pathologic evaluations among healthcare professionals.
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Nearly a third of patients with primary lung cancer present with malignant central airway obstruction (MCAO), and some of them appear to have advanced disease. In these patients, accurate staging is crucial. Although the literature extensively outlines the role of interventional bronchoscopy in palliation, its contribution to refining the staging of patients with MCAO is noteworthy.

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Background: Rosai-Dorfman disease is a rare condition that typically presents as a nodal disease. Cardiac involvement is extremely uncommon, occurring in 0.1-0.

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  • A study found that up to 15% of lung cancer patients have multiple suspicious nodules, and some of these may actually be multiple primary lung cancers (SMPLC), which is currently increasing in incidence.* -
  • In a review of 227 patients who underwent lung cancer surgery, 20.7% were identified as having SMPLC, primarily with distinct tumors and good survival rates over four years.* -
  • The research highlights the importance for surgeons to recognize SMPLC to ensure patients receive appropriate treatment, as misdiagnosis can lead to less effective stage-based care.*
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Neuraxial anesthesia (NA) has been contraindicated in patients with aortic stenosis (AS) due to concerns of sympathetic blockade and hemodynamic instability. These considerations are based on precautionary expert recommendations, supported by expected physiologic effects, but in the absence of any published scientific evidence. In light of the increasing elderly population and the prevalence of AS, this systematic review compiles available literature on NA in patients with AS to address the understanding of the anesthetic practice and safety in this population.

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Pulmonary arteriovenous malformations (PAVMs) can be asymptomatic or result in a range of complications such as brain abscesses or cryptogenic emboli, which can contribute to morbidity and mortality if not diagnosed and treated in a timely manner. To date, there have been several reports of delayed diagnosis of PAVMs, which have been largely attributed to the misconception that PAVMs are too rare to be of clinical significance. Furthermore, because intracardiac shunting secondary to a patent foramen ovale (PFO) or atrial septal defect (ASD) also results in a positive saline contrast study with echocardiography, PAVM can be easily misdiagnosed as an intracardiac right-toleft shunt.

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Objectives: Transesophageal echocardiography-related complications (TEE-RC) are higher in structural heart interventions than in traditional operative settings. In mitral valve transcatheter edge-to-edge repair (MV-TEER), the incidence of TEE-RC may be higher than in other structural interventions. However, existing reports are limited and robust data evaluating TEE safety in this patient population are lacking.

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In patients undergoing percutaneous cardiac interventions, perioperative transesophageal echocardiography is used routinely, often revealing an unusual pathology that was not previously detected with transthoracic echocardiography. In this e-challenge, the authors present a patient undergoing percutaneous transcatheter aortic valve replacement, with preprocedural transesophageal echocardiography revealing an abnormal color Doppler signal near the left main coronary artery during diastole.

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Aortic valve repair (AVr) aims to preserve the native aortic leaflets and restore normal valve function. In doing so, AVr is a more technically challenging approach than traditional aortic valve replacement. Some of the complexity of repair techniques can be attributed to the unique structure of the functional aortic annulus (FAA), which, unlike the well-defined mitral annulus, is comprised of virtual and functional components.

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