Consolidating exposure scenario information for mixtures--experiences and challenges.

Introduction: The requirements of the European Union Regulation on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), including the preparation of exposure scenarios for the communication of safe use, are focused on single substances. Since the chemical products used at workplaces are typically mixtures, it is important to ensure that accurate information is available regarding their safe use. The focus of the present study was on the methods for consolidating (combining) the information presented in the exposure scenarios of the individual components of a mixture.