Publications by authors named "Nigusse Tesfay"

Article Synopsis
  • Therapeutic inertia is the reluctance of healthcare providers to escalate treatment for patients with poorly controlled hypertension, even when guidelines suggest otherwise, and it has become a key reason for inadequate hypertension management.
  • This study aimed to explore the prevalence and causes of therapeutic inertia specifically among ambulatory patients with hypertension at a cardiac clinic in northern Ethiopia, involving 282 participants tracked over six months.
  • The findings revealed that 72% of participants with uncontrolled hypertension experienced therapeutic inertia, leading to recommendations for increased medication dose or the introduction of additional drugs to improve treatment outcomes.
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Background: Although antiseizure medications play a crucial role in the management of epilepsy, their benefit can be compromised due to drug-related problems. Drug therapy problems can lead to poor seizure control, reduced quality of life, and increased morbidity and mortality in patients with epilepsy. However, in our setting, there is limited knowledge about drug therapy problems and the factors that contribute to them.

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Background: Antibiotic use related problems lead to the emergence of resistance, failure of therapy, morbidity, mortality, and unnecessary healthcare expenditure. However, little is known about antimicrobial use related problems in our setting particularly in hospitalized surgical patients.

Objective: The purpose of this study was to investigate antibiotic use related problems and their determinants among hospitalized surgical patients.

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