Publications by authors named "Nighat Majeed"
Article Synopsis
- A clinical trial in Pakistan tested the effects of honey and Nigella sativa on COVID-19 patients, showing significant improvements compared to a placebo.
- Patients receiving the treatment experienced a faster reduction in symptoms and quicker viral clearance, with moderate cases recovering in an average of 4 days versus 7 days for the placebo group.
- The treatment also led to a lower mortality rate in severe cases (4%) compared to those on placebo, who had a mortality rate over 15%.
Objectives: Considering the therapeutic potential of honey and Nigella sativa (HNS) in coronavirus disease 2019 (COVID-19) patients, the objective of the study is defined to evaluate the prophylactic role of HNS.
Trial Design: The study is a randomized, placebo-controlled, adaptive clinical trial with parallel group design, superiority framework with an allocation ratio of 1:1 among experimental (HNS) and placebo group. An interim analysis will be done when half of the patients have been recruited to evaluate the need to adapt sample size, efficacy, and futility of the trial.
Objectives: The study objective is to quantify the effectiveness of ivermectin (subcutaneous/oral IVM) in the presence or absence of zinc (Zn) for clinical and radiological improvement in coronavirus disease 2019 (COVID-19) patients with moderate severity.
Trial Design: This quadruple-blinded, placebo-controlled randomized clinical trial will be a multiarmed multi-centered study with superiority framework.
Participants: Quinquagenarian and sexagenarian patients with moderate COVID-19 symptoms and positive severe respiratory syndrome coronavirus -2 (SARS-CoV-2) PCR will be included.