Publications by authors named "Nigel Osborne"

We propose for autism: a system of supports for friends, therapists, parents, and educators; a system which aims to augment bidirectional communication and complement existing therapeutic approaches. We begin by summarizing the developmental significance of and the challenges observed in early autism. Meta-analyses conclude the early primacy of such challenges, yet cite the lack of focused therapies.

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Human cultures educate children with different strategies. Ancient hunter-gatherers 200,000 years ago, with bodies and brains like our own, in bands of a hundred well-known individuals or less, depended on spontaneous cooperative practice of knowledge and skills in a natural world. Before creating language, they appreciated beautiful objects and music.

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Article Synopsis
  • The study aimed to detail the clinical and imaging characteristics of four new families with childhood cases of COL4A1 mutation.
  • Four children, three boys and one girl, presented symptoms such as recurrent strokes, hemiplegia, and developmental delays, along with additional features like cataracts.
  • MRI scans indicated notable brain changes, and new mutations in the COL4A1 gene were discovered, suggesting these mutations often lead to serious neurological issues in affected children.
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Recent developments in music neuroscience are considered a source for reflection on, and evaluation and development of, musical therapeutic practice in the field, in particular, in relation to traumatized children and postconflict societies. Music neuroscience research is related to practice within a broad biopsychosocial framework. Here, examples are detailed of work from North Uganda, Palestine, and South Thailand.

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Objectives: To assess the feasibility and results of trans-axillary approach for balloon aortic valvoplasty (BAV) in early infancy.

Background: Severe aortic valve stenosis (SAVS) is rare but serious condition in infancy, which may be promptly treated either by surgical aortic valvotomy or BAV. BAV is usually performed via the femoral artery route, which is associated with significant vascular complications and long procedure times.

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