Publications by authors named "Nigel Ab Simpson"
Health Technol Assess
August 2024
Article Synopsis
- Second trimester miscarriage and preterm birth are significant issues globally, leading to the use of surgical cervical cerclage to help prevent these outcomes, with a focus on comparing the effectiveness of monofilament versus braided sutures.
- The study aims to determine if monofilament sutures reduce pregnancy loss better than braided ones in women needing cervical cerclage, as bacteria colonization on braided sutures may contribute to complications.
- Conducted across 75 UK maternity sites, this open randomized controlled trial includes women with specific risk factors for preterm birth and evaluates outcomes like miscarriage rates and perinatal mortality through a 1:1 randomization process.
