Publications by authors named "Niexing Tang"
Cell Host Microbe
December 2024
Article Synopsis
- Cholestatic liver disease (CLD) is a prevalent liver disorder with few treatment options, but zinc (Zn) supplementation may improve the situation by altering the gut microbiome.
- In this study, Zn was found to increase levels of the bacteria Blautia producta and the compound p-coumaric acid, which were associated with reduced liver injury in both mice and humans.
- The protective effects of Zn against liver damage were linked to p-coumaric acid's ability to inhibit oxidative stress in liver cells, illustrating a beneficial interaction between the host's gut microbiome and Zn supplementation in managing CLD.
