The effectiveness of natural and synthetic immunomodulators in the treatment of inflammatory bowel disease in dogs.

The aim of the study was to evaluate the usefulness of immunomodulators in the treatment of inflammatory bowel disease (IBD) in dogs. Twenty-eight dogs diagnosed with IBD took part in the study. The animals received a food containing extruded immunomodulators: β-1,3/1,6-D-glucan, β-hydroxy-β-methyl-butyrate (HMB) and levamisole for 42 days.

A correlation between the canine Inflammatory Bowel Disease Activity Index score and the histopathological evaluation of the small intestinal mucosa in canine inflammatory bowel disease.

The aim of this study was to assess the degree of correlation between the intensity of clinical symptoms and the macroscopic and histopathological evaluation of the small intestinal mucous membrane in dogs. The results point to a statistically significant correlation between the values of the CIBDAI index and the histopathological assessment of the duodenum mucous membrane in patients with minor and moderate intensity of the disease. The lowest correlation coefficient was obtained for the indicator comparing macroscopic and histopathological evaluations.

A population of nesfatin 1-like immunoreactive (LI) cells in the mucosal layer of the canine digestive tract.

The aim of this study was to investigate for the first time nesfatin-1-like immunoreactive (LI) cells in the mucosal layer of the canine digestive tract. Distribution of nesfatin-1 - LI cell bodies and the co-localization of nesfatin-1 with somatostatin (SOM), cocaine-and amphetamine-regulated transcript peptide (CART), protein gene product 9.5 (PGP 9.

Treatment of inflammatory bowel disease (IBD) in dogs and cats.

The treatment of inflammatory bowel disease (IBD) possesses numerous difficulties owing to the unclear etiology of the disease. This article overviews the drugs used in the treatment of IBD depending on the intensity of clinical symptoms (Canine Inflammatory Bowel Disease Activity Index and Canine Chronic Enterophaty Clinical Activity Index). Patients demonstrating mild symptoms of the disease are usually placed on an appropriate diet which may be combined with immunomodulative or probiotic treatment.

Usefulness of laparoscopy guided renal biopsy in dogs.

Renal biopsies were carried out in 25 mixed-breed dogs of both sexes, aged 6 to 11 years, using an automatic, laparoscopy-guided method. The aim of the study was to apply and evaluate the usefulness of this technique in the diagnosis of renal pathologies in dogs. Twenty biopsy specimens were obtained from the right kidney and five--from the left kidney.

Contrast-enhanced ultrasonography (CEUS) in canine liver examination.

Ultrasonography is a noninvasive diagnostic tool used to image size, shape, parenchyma and vascularization of various body organs. Unfortunately, the ultrasonographic image is characterized by a low contrast due to similar acoustic properties of the soft tissue. The Doppler mode provides information about blood flow, but is incapable of imaging small vessels and capillaries because of their low blood flow velocity (1 mm/s).

Macroscopic and histopathological examination of the gastric mucosa in dogs with inflammatory bowel disease (IBD) treated with mesalazine.

The objective of this study was to carry out a macroscopic and histopathological examination of the gastric mucosa in dogs with inflammatory bowel disease and to evaluate the effect of mesalazine therapy on histopathological changes in the gastric mucosa. The treatment was performed on 18 dogs with histopathologically confirmed inflammation of the duodenum and the jejunum. The animals were administered mesalazine at 12.

Usefulness of endoscopic examination for the diagnosis of inflammatory bowel disease in the dog.

The usefulness of endoscopic examination for the diagnosis and treatment of chronic enteritis in dogs was determined in this study. It was demonstrated, based on a clinical case, that endoscopy is essential for IBD diagnosis in dogs. Endoscopy also helps to estimate the efficiency of the treatment strategy applied.